Abstract
The process of analysing metabolic pathways mathematically in systems biology requires accurate parameters which represent the simulated in-vivo processes. Differential Evolution algorithm (DE) has been provenable to outperform other estimation algorithms, and has been used to achieve an accurate estimation of the required parameters. The total number of DE-variants has increased recently, which makes researchers face difficulties in obtaining complete overview of current DE-variants. To provide a holistic view to the area of mathematical modelling in System Biology, through this paper, we present an overview of modelling methods, parameter estimation by utilizing DE-variants to analyse metabolic pathways, and exiting pathway simulation software.
Keywords: Differential evolution, modelling, system biology.
Current Bioinformatics
Title:A Review on Modelling Methods, Pathway Simulation Software and Recent Development on Differential Evolution Algorithms for Metabolic Pathways in Systems Biology
Volume: 9 Issue: 5
Author(s): Chuii Khim Chong, Mohd Saberi Mohamad, Safaai Deris, Mohd Shahir Shamsir, Yee Wen Choon and Lian En Chai
Affiliation:
Keywords: Differential evolution, modelling, system biology.
Abstract: The process of analysing metabolic pathways mathematically in systems biology requires accurate parameters which represent the simulated in-vivo processes. Differential Evolution algorithm (DE) has been provenable to outperform other estimation algorithms, and has been used to achieve an accurate estimation of the required parameters. The total number of DE-variants has increased recently, which makes researchers face difficulties in obtaining complete overview of current DE-variants. To provide a holistic view to the area of mathematical modelling in System Biology, through this paper, we present an overview of modelling methods, parameter estimation by utilizing DE-variants to analyse metabolic pathways, and exiting pathway simulation software.
Export Options
About this article
Cite this article as:
Chong Khim Chuii, Mohamad Saberi Mohd, Deris Safaai, Shamsir Shahir Mohd, Choon Wen Yee and Chai En Lian, A Review on Modelling Methods, Pathway Simulation Software and Recent Development on Differential Evolution Algorithms for Metabolic Pathways in Systems Biology, Current Bioinformatics 2014; 9 (5) . https://dx.doi.org/10.2174/157489360905141014154242
DOI https://dx.doi.org/10.2174/157489360905141014154242 |
Print ISSN 1574-8936 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-392X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Hyperhomocysteinaemia: A Critical Review of Old and New Aspects
Current Drug Metabolism Can Non-invasive Biomarkers Lead to an Earlier Diagnosis of Alzheimer’s Disease?
Current Alzheimer Research NLRP3 Inflammasome in the Pathophysiology of Hemorrhagic Stroke: A Review
Current Neuropharmacology Effects of Perfluorocarbon Dodecafluoropentane (NVX-108) on Cerebral Microvasculature in the Healthy Rat
Current Drug Discovery Technologies The Many Roles of Chemokine Receptors in Neurodegenerative Disorders: Emerging New Therapeutical Strategies
Current Medicinal Chemistry Pleiotropic Effects of Nitric Oxide on SARS-CoV-2 Infections
Coronaviruses Flavonoids from Stem and Leaf of <i>Scutellaria Baicalensis</i> Georgi Inhibit the Phosphorylation on Multi-sites of Tau Protein Induced by Okadaic Acid and the Regulative Mechanism of Protein Kinases in Rats
Combinatorial Chemistry & High Throughput Screening Meet Our Editor:
Current Hypertension Reviews Cardiovascular Risk in Psoriasis: Current State of the Art
Current Vascular Pharmacology Nose-to-brain Delivery of Natural Compounds for the Treatment of Central Nervous System Disorders
Current Pharmaceutical Design Cerebral Palsy: Classification, Etiology and Evolution of Spine Deformity in Children and Adolescents
Current Pediatric Reviews Editorial: Current Strategies in Targeting Brain Disorders
CNS & Neurological Disorders - Drug Targets Should the Status of the Pathway Mediated by BRCA1 and BRCA2 be Evaluated Before Selecting Cancer Chemotherapy Drugs?
Current Pharmacogenomics Low Density Lipoprotein Receptor-Related Proteins (LRPs), Alzheimers and Cognition
Current Drug Targets - CNS & Neurological Disorders The Biochemical and Physical Process of Fibrinolysis and Effects of Clot Structure and Stability on the Lysis Rate
Cardiovascular & Hematological Agents in Medicinal Chemistry Recent Update on the Alzheimer's Disease Progression, Diagnosis and Treatment Approaches
Current Drug Targets The Diagnostic Utility of Pleural Fluid Tests in Clinical Practice
Current Respiratory Medicine Reviews Regulatory Triangle of Neurodegeneration, Adult Neurogenesis and MicroRNAs
CNS & Neurological Disorders - Drug Targets Chemokine Contribution in Stem Cell Engraftment into the Infarcted Myocardium
Current Stem Cell Research & Therapy A Novel Neuroimaging Model to Predict Early Neurological Deterioration After Acute Ischemic Stroke
Current Neurovascular Research