Abstract
Patients with chronic heart failure have prolonged sympathetic stimulation and subsequent worsening of the failing heart function. Beta-blockers (non-selective, cardio-selective, and non-selective with ancillary properties) counteract the effects of prolonged sympathetic stimulation. Beta-blocker therapy results in the improvement of the left ventricular systolic and diastolic function, reversal remodeling, heart rate control, effective prevention of the malignant arrhythmias, and lowering of the both cardiac afterload and preload in patients with chronic heart failure.
Keywords: Beta-blockers, mechanisms, childhood, heart failure.
Reviews on Recent Clinical Trials
Title:Mechanisms of Beta-Blockers Action in Patients with Heart Failure
Volume: 9 Issue: 2
Author(s): Sergej Prijic and Reiner Buchhorn
Affiliation:
Keywords: Beta-blockers, mechanisms, childhood, heart failure.
Abstract: Patients with chronic heart failure have prolonged sympathetic stimulation and subsequent worsening of the failing heart function. Beta-blockers (non-selective, cardio-selective, and non-selective with ancillary properties) counteract the effects of prolonged sympathetic stimulation. Beta-blocker therapy results in the improvement of the left ventricular systolic and diastolic function, reversal remodeling, heart rate control, effective prevention of the malignant arrhythmias, and lowering of the both cardiac afterload and preload in patients with chronic heart failure.
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Cite this article as:
Prijic Sergej and Buchhorn Reiner, Mechanisms of Beta-Blockers Action in Patients with Heart Failure, Reviews on Recent Clinical Trials 2014; 9 (2) . https://dx.doi.org/10.2174/1574887109666140908125402
DOI https://dx.doi.org/10.2174/1574887109666140908125402 |
Print ISSN 1574-8871 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-1038 |
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