Abstract
There is emerging recognition of the need for continuous long term electrographic monitoring of the encephalopathic neonate. While full-montage EEG with video remains the gold standard for monitoring, it is limited in application due to the complexity of lead application and specialized interpretation of results. Amplitude integrated EEG (aEEG) is derived from limited channels (usually C3-P3, C4-P4) and is filtered, rectified and time-compressed to serve as a bedside electrographic trend monitor. It’s simple application and interpretation has resulted in increasing use in neonatal units across the world. Validation studies with full montage EEG have shown reliable results in interpretation of EEG background and electrographic seizures, especially when used with the simultaneously displayed raw EEG trace. Several aEEG monitors are commercially available and seizure algorithms are being developed for use on these monitors. These aEEG monitors, complement conventional EEG and offer a significant advance in the feasibility of long term electrographic monitoring of the encephalopathic neonate.
Keywords: aEEG, neonatal encephalopathy, hypoxic-ischemic encephalopathy, neonatal seizures, electroencephalography, neurodevelopmental outcome.
Current Pediatric Reviews
Title:Amplitude-Integrated EEG and the Newborn Infant
Volume: 10 Issue: 1
Author(s): Divyen K. Shah and Amit Mathur
Affiliation:
Keywords: aEEG, neonatal encephalopathy, hypoxic-ischemic encephalopathy, neonatal seizures, electroencephalography, neurodevelopmental outcome.
Abstract: There is emerging recognition of the need for continuous long term electrographic monitoring of the encephalopathic neonate. While full-montage EEG with video remains the gold standard for monitoring, it is limited in application due to the complexity of lead application and specialized interpretation of results. Amplitude integrated EEG (aEEG) is derived from limited channels (usually C3-P3, C4-P4) and is filtered, rectified and time-compressed to serve as a bedside electrographic trend monitor. It’s simple application and interpretation has resulted in increasing use in neonatal units across the world. Validation studies with full montage EEG have shown reliable results in interpretation of EEG background and electrographic seizures, especially when used with the simultaneously displayed raw EEG trace. Several aEEG monitors are commercially available and seizure algorithms are being developed for use on these monitors. These aEEG monitors, complement conventional EEG and offer a significant advance in the feasibility of long term electrographic monitoring of the encephalopathic neonate.
Export Options
About this article
Cite this article as:
Shah K. Divyen and Mathur Amit, Amplitude-Integrated EEG and the Newborn Infant, Current Pediatric Reviews 2014; 10 (1) . https://dx.doi.org/10.2174/157339631001140408115859
DOI https://dx.doi.org/10.2174/157339631001140408115859 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
2015 Update of Erectile Dysfunction Management Following Radical Prostatectomy: From Basic Research to Clinical Management
Current Pharmaceutical Design The Metabolic Approach in Patients with Heart Failure: Effects on Left Ventricle Remodeling
Current Pharmaceutical Design Interplay between Epigenetics & Cancer Metabolism
Current Pharmaceutical Design Endothelial Colony Forming Capacity is Related to C-Reactive Protein Levels in Healthy Subjects
Current Neurovascular Research Inhibition of Disulfide Reductases as a Therapeutic Strategy
Current Enzyme Inhibition Group I Metabotropic Glutamate Receptor Signalling and its Implication in Neurological Disease
CNS & Neurological Disorders - Drug Targets Sequence and Structural Elements in the Mechanism of Function of Rhodopsin-Like Family of G Protein-Coupled-Receptors
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery Recent Advances on Radionuclide Labeled Hypoxia-Imaging Agents
Current Pharmaceutical Design Using Nutrigenomics to Evaluate Apoptosis as a Preemptive Target in Cancer Prevention
Current Cancer Drug Targets MicroRNAs as Cancer Biomarkers
MicroRNA Combining Angiogenesis Inhibitors with Radiation: Advances and Challenges in Cancer Treatment
Current Pharmaceutical Design Conjugates of Natural Compounds with Nitroxyl Radicals as a Basis for Creation of Pharmacological Agents of New Generation
Current Medicinal Chemistry Inhalation Gases or Gaseous Mediators As Neuroprotectants for Cerebral Ischaemia
Current Drug Targets Modulation of Gene Transcription by Natural Products - A Viable Anticancer Strategy
Current Pharmaceutical Design The Gut and Intestinal Bacteria in Chronic Heart Failure
Current Drug Metabolism Xanthine Oxidoreductase in Drug Metabolism: Beyond a Role as a Detoxifying Enzyme
Current Medicinal Chemistry Current Developments of Coumarin Compounds in Medicinal Chemistry
Current Pharmaceutical Design Capsaicin Sensitive-Sensory Nerves and Blood Pressure Regulation
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Angiogenesis Inhibitors and Vascular Disrupting Agents in Non-Small Cell Lung Cancer
Current Medicinal Chemistry Neuroprotection by Resveratrol in Diabetic Neuropathy: Concepts & Mechanisms
Current Medicinal Chemistry