Abstract
Peripheral pulmonary nodules can present diagnostic challenges, especially in high risk patients. Surgical biopsy is the gold standard for establishing a diagnosis and can often serve as definitive treatment; however, there are associated risks, morbidities, and costs, which may be too high, especially if the result is a benign lesion. Bronchoscopy (with or without fluoroscopy) or imaging guided transthoracic needle aspiration can often determine the diagnosis in appropriate patients; navigational aids can often improve the yield of bronchoscopic biopsy. Navigational bronchoscopy guides the user to the lesion(s) of interest using computer software integrated with computed tomography images and an electromagnetic field generated around the patient. While this is a relatively new technology, several studies have demonstrated the efficacy and safety of the procedure. Navigational bronchoscopy is best used, along with transthoracic needle aspiration, endobronchial ultrasound (including radial probe), and surgical interventions, as part of a step-wise diagnostic approach to the evaluation of a peripheral pulmonary nodule.
Keywords: Diagnosis, navigational bronchoscopy, pulmonary nodule.
Current Respiratory Medicine Reviews
Title:Navigational Bronchoscopy in the Evaluation of the Peripheral Pulmonary Nodule.
Volume: 10 Issue: 1
Author(s): Zuheir Kassabo, Fletcher Pierce and Sean Hesselbacher
Affiliation:
Keywords: Diagnosis, navigational bronchoscopy, pulmonary nodule.
Abstract: Peripheral pulmonary nodules can present diagnostic challenges, especially in high risk patients. Surgical biopsy is the gold standard for establishing a diagnosis and can often serve as definitive treatment; however, there are associated risks, morbidities, and costs, which may be too high, especially if the result is a benign lesion. Bronchoscopy (with or without fluoroscopy) or imaging guided transthoracic needle aspiration can often determine the diagnosis in appropriate patients; navigational aids can often improve the yield of bronchoscopic biopsy. Navigational bronchoscopy guides the user to the lesion(s) of interest using computer software integrated with computed tomography images and an electromagnetic field generated around the patient. While this is a relatively new technology, several studies have demonstrated the efficacy and safety of the procedure. Navigational bronchoscopy is best used, along with transthoracic needle aspiration, endobronchial ultrasound (including radial probe), and surgical interventions, as part of a step-wise diagnostic approach to the evaluation of a peripheral pulmonary nodule.
Export Options
About this article
Cite this article as:
Kassabo Zuheir, Pierce Fletcher and Hesselbacher Sean, Navigational Bronchoscopy in the Evaluation of the Peripheral Pulmonary Nodule., Current Respiratory Medicine Reviews 2014; 10 (1) . https://dx.doi.org/10.2174/1573398X10666140402222327
DOI https://dx.doi.org/10.2174/1573398X10666140402222327 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
An Overview on Keratinocyte Growth Factor: From the Molecular Properties to Clinical Applications
Protein & Peptide Letters Protein-protein Interactions: Network Analysis and Applications in Drug Discovery
Current Pharmaceutical Design Evaluation of Polygonum bistorta for Anticancer Potential Using Selected Cancer Cell Lines
Medicinal Chemistry Experimental and Computational Approaches to Improve Binding Affinity in Chemical Biology and Drug Discovery
Current Topics in Medicinal Chemistry Machine Learning Based Support System for Students to Select Stream (Subject)
Recent Advances in Computer Science and Communications Recent Progress of Small Molecular VEGFR Inhibitors as Anticancer Agents
Mini-Reviews in Medicinal Chemistry Bugs as Drugs: Understanding the Linkage between Gut Microbiota and Cancer Treatment
Current Drug Targets Immunomodulation Mechanism of Antidepressants: Interactions between Serotonin/Norepinephrine Balance and Th1/Th2 Balance
Current Neuropharmacology Evaluation of Melatonin Effect on Human Breast Cancer Stem Cells Using a Threedimensional Growth Method of Mammospheres
Anti-Cancer Agents in Medicinal Chemistry Salidroside - Can it be a Multifunctional Drug?
Current Drug Metabolism Possible Selective Cytotoxicity of Vanadium Complex on Breast Cancer Cells Involving Pathophysiological Pathways
Anti-Cancer Agents in Medicinal Chemistry Overcoming Drug Resistance and Treating Advanced Prostate Cancer
Current Drug Targets Patenting Human Genes and Stem Cells
Recent Patents on DNA & Gene Sequences Atmospheric Concentrations of Polycyclic Aromatic Hydrocarbons (PAHs) in India and South Korea: A Review
Mini-Reviews in Organic Chemistry 2D QSAR and Virtual Screening based on Pyridopyrimidine Analogs of Epidermal Growth Factor Receptor Tyrosine Kinase
Current Computer-Aided Drug Design ErbB Targeted Drugs and Angiogenesis
Current Vascular Pharmacology Immune Checkpoint Inhibitors: Basics and Challenges
Current Medicinal Chemistry DNA Methylation: A Possible Target for Current and Future Studies on Cancer?
Epigenetic Diagnosis & Therapy (Discontinued) Ceramide: Therapeutic Potential in Combination Therapy for Cancer Treatment
Current Drug Metabolism The Application of Optical Technology in Microfluidic Systems
Current Proteomics