Abstract
MRI plays a unique role in cancer treatment from three perspectives: Firstly, MRI has superior soft tissue resolution, which makes it indispensible in delineating, staging and monitoring treatment efficacy for certain tumors; Secondly, several techniques which use real-time MRI to map such physiological parameters as temperature, water content or pH have been developed to guide course of anticancer therapies; Thirdly, different targeted probes or hybrid nanoparticles are being developed to facilitate the diagnosis and treatment of tumor under guidance of MRI. In this review article, we will briefly review the first two aspects of MRI guided cancer therapy, followed by a more comprehensive review on the third part focusing on targeted MR imaging probes for personalized medicine.
Keywords: Cancer, Intervention, Image-guided, Molecular imaging, Magnetic Resonance Imaging, Molecular probe.
Current Pharmaceutical Biotechnology
Title:Cancer Diagnosis and Treatment Guidance: Role of MRI and MRI Probes in the Era of Molecular Imaging
Volume: 14 Issue: 8
Author(s): Jingjing Lu, Feng Feng and Zhengyu Jin
Affiliation:
Keywords: Cancer, Intervention, Image-guided, Molecular imaging, Magnetic Resonance Imaging, Molecular probe.
Abstract: MRI plays a unique role in cancer treatment from three perspectives: Firstly, MRI has superior soft tissue resolution, which makes it indispensible in delineating, staging and monitoring treatment efficacy for certain tumors; Secondly, several techniques which use real-time MRI to map such physiological parameters as temperature, water content or pH have been developed to guide course of anticancer therapies; Thirdly, different targeted probes or hybrid nanoparticles are being developed to facilitate the diagnosis and treatment of tumor under guidance of MRI. In this review article, we will briefly review the first two aspects of MRI guided cancer therapy, followed by a more comprehensive review on the third part focusing on targeted MR imaging probes for personalized medicine.
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Cite this article as:
Lu Jingjing, Feng Feng and Jin Zhengyu, Cancer Diagnosis and Treatment Guidance: Role of MRI and MRI Probes in the Era of Molecular Imaging, Current Pharmaceutical Biotechnology 2013; 14 (8) . https://dx.doi.org/10.2174/1389201014666131226105916
DOI https://dx.doi.org/10.2174/1389201014666131226105916 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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