Abstract
Swine flu and avian flu outbreaks have occurred in recent years in addition to seasonal flu. As mortality rate records are not available at the early stage of an outbreak, two parameters may be useful to assess the viral virulence : 1. the time required for the first domestic case in a newly involved region, and 2. the doubling time of new infected cases. Viral virulence is one of the most important factors in guiding short term and immediate responses. Although routine surveillance and repeated vaccination are useful efforts, some novel strategies that may be relevant to prevent and control the spread of influenza among human beings and domestic animals are discussed.
Keywords: Avian flu, Viral virulence, Gene knockout, Sia, 3 receptors and Sia, 6 receptors.
Current Pharmaceutical Biotechnology
Title:Understanding of and Possible Strategies to Avian Influenza Outbreak
Volume: 14 Issue: 8
Author(s): Junkang Shen, Andy Zhang, Huifen Xu, Pierre Sirois, Jia Zhang, Kai Li and Li Xiao
Affiliation:
Keywords: Avian flu, Viral virulence, Gene knockout, Sia, 3 receptors and Sia, 6 receptors.
Abstract: Swine flu and avian flu outbreaks have occurred in recent years in addition to seasonal flu. As mortality rate records are not available at the early stage of an outbreak, two parameters may be useful to assess the viral virulence : 1. the time required for the first domestic case in a newly involved region, and 2. the doubling time of new infected cases. Viral virulence is one of the most important factors in guiding short term and immediate responses. Although routine surveillance and repeated vaccination are useful efforts, some novel strategies that may be relevant to prevent and control the spread of influenza among human beings and domestic animals are discussed.
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Cite this article as:
Shen Junkang, Zhang Andy, Xu Huifen, Sirois Pierre, Zhang Jia, Li Kai and Xiao Li, Understanding of and Possible Strategies to Avian Influenza Outbreak, Current Pharmaceutical Biotechnology 2013; 14 (8) . https://dx.doi.org/10.2174/13892010113146660233
DOI https://dx.doi.org/10.2174/13892010113146660233 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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