Abstract
An efficient synthesis of 2-substituted benzoxazoles via copper acetate monohydrate oxidative coupling of aldehydes with o-aminophenol is described. This synthetic strategy has some advantages as simple procedure, inexpensive and easily available catalyst, and facile isolation of the products in moderate to good yields.
Keywords: Benzoxazoles, aromatic aldehydes, o-aminophenol, copper acetate monohydrate, oxidative cyclization.
Letters in Organic Chemistry
Title:One-pot Synthesis of 2-Substituted Benzoxazoles Promoted by Copper Acetate Monohydrate
Volume: 11 Issue: 3
Author(s): Guo-Feng Chen, Hai-Dong Shen, Li-Yan Zhang, Hong-Yang Li, Rui-Jia Lan, Bao-Hua Chen, Ji-Tai Li and Qing-Hui Hu
Affiliation:
Keywords: Benzoxazoles, aromatic aldehydes, o-aminophenol, copper acetate monohydrate, oxidative cyclization.
Abstract: An efficient synthesis of 2-substituted benzoxazoles via copper acetate monohydrate oxidative coupling of aldehydes with o-aminophenol is described. This synthetic strategy has some advantages as simple procedure, inexpensive and easily available catalyst, and facile isolation of the products in moderate to good yields.
Export Options
About this article
Cite this article as:
Chen Guo-Feng, Shen Hai-Dong, Zhang Li-Yan, Li Hong-Yang, Lan Rui-Jia, Chen Bao-Hua, Li Ji-Tai and Hu Qing-Hui, One-pot Synthesis of 2-Substituted Benzoxazoles Promoted by Copper Acetate Monohydrate, Letters in Organic Chemistry 2014; 11 (3) . https://dx.doi.org/10.2174/15701786113106660070
DOI https://dx.doi.org/10.2174/15701786113106660070 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Histamine H4 Receptor: A Novel Therapeutic Target for Immune and Allergic Responses
Mini-Reviews in Medicinal Chemistry Editorial [Hot topic: Cognitive Enhancing Drugs: A Blessing for Society? (Joris C. Verster)]
Current Drug Abuse Reviews Theoretical Modeling of HPV: QSAR and Novodesign with Fragment Approach
Current Computer-Aided Drug Design Plasmalogens in Biological Systems: Their Role in Oxidative Processes in Biological Membranes, their Contribution to Pathological Processes and Aging and Plasmalogen Analysis
Current Medicinal Chemistry Influence of the Bystander Effect on HSV-tk / GCV Gene Therapy. A Review.
Current Gene Therapy Epigenetics in Alzheimers Disease: a Focus on DNA Modifications
Current Pharmaceutical Design High Cytotoxicity and Apoptotic Effects of Natural Bioactive Benzofuran Derivative on the MCF-7 Breast Cancer Cell Line
Combinatorial Chemistry & High Throughput Screening Inhibiting Protein-Protein Interactions as an Emerging Paradigm for Drug Discovery
Mini-Reviews in Medicinal Chemistry Electrochemistry of Alzheimer Disease Amyloid Beta Peptides
Current Medicinal Chemistry Lipids in the Diet and the Fatty Acid Profile in Beef: A Review and Recent Patents on the Topic
Recent Patents on Food, Nutrition & Agriculture Emerging Targets and Latest Proteomics Based Therapeutic Approaches in Neurodegenerative Diseases
Current Protein & Peptide Science Tau Pathology and Future Therapeutics
Current Alzheimer Research Photo-triggered Drug Delivery Systems for Neuron-related Applications
Current Medicinal Chemistry Multiple Sclerosis: Pathogenesis and Treatment
Current Neuropharmacology Activity-dependent Synaptic Plasticity and Metaplasticity in Spinal Motor Networks
Current Pharmaceutical Design Gauging Reactive Metabolites in Drug-Induced Toxicity
Current Medicinal Chemistry From Cocaine to Ropivacaine: The History of Local Anesthetic Drugs
Current Topics in Medicinal Chemistry Neuroprotection by Estrogen and Progesterone in Traumatic Brain Injury and Spinal Cord Injury
Current Neuropharmacology The Impact of CRISPR/Cas9-Based Genomic Engineering on Biomedical Research and Medicine
Current Molecular Medicine Short-Term Ultramicronized Palmitoylethanolamide Therapy in Patients with Myasthenia Gravis: a Pilot Study to Possible Future Implications of Treatment
CNS & Neurological Disorders - Drug Targets