Abstract
Supercritical fluid extraction (SFE) has been a widely studied green technology to obtain triterpenoids (TTs) enriched extracts from various vegetable matrices.
This review covers research advances regarding the SFE of TTs, with emphasis on biomass sources, operating conditions and their optimization, and modeling. As in other applications of the supercritical technology, carbon dioxide is the common solvent adopted, being generally modified with small amounts of cosolvents (e.g. ethanol, methanol) to increase TTs solubility, as many of these molecules are polar. The operating conditions reported for the SFE of TTs from biomass lie between 40 and 90°C, 100 and 500 bar, and 0 and 5 wt. % of modifier. An extensive list of relevant works in this field is also provided, where the most important experimental and/or theoretical information is presented.
Exploitation is also addressed through a compilation of registered patents on TTs extraction and purification, particularly on strategies to concentrate these compounds after organic solvent or supercritical carbon dioxide extraction. In the whole, there is a research and intellectual property basis to support further industrial attempts to implement processes combining SFE and purification technologies for TTs production.
Keywords: Supercritical fluid extraction, triterpenoids, triterpenic acids, purification, patents.
Call for Papers in Thematic Issues
Applications of Molecular Descriptors in Physicochemical Properties Research of Organic Compounds
Chemical graph theory is concerned with all aspects of the application of graph theory to various areas of chemistry, including organic, theoretical, mathematical, and computational chemistry, as well as in bioinformatics and computational biology. By the use of the term chemical it is emphasized that one is allowed in chemical ...read more
Navigating the 2D Universe in Organic Chemistry
This special issue explores the transformative impact of two-dimensional (2D) materials on the realm of organic chemistry, unraveling new possibilities for synthesis, functionalization, and applications of organic compounds. Focused on the unique chemistry within this novel dimension, the issue highlights breakthroughs in the field of 2D organic chemistry. Contributions are ...read more
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
33