Abstract
A high efficient and environmentally friendly procedure for the production of bis thiazolidinones has been developed. This synthetic approach involves the simple condensation of an appropriate dialdehyde and N,N'-diarylthioureas with chloroacetyl chloride in eutectic salts as a promoter and solvent at 80 °C. All products were obtained in good to excellent yields. Structures of these compounds were established on the basis of IR, 1H-NMR, 13C-NMR and by elemental analysis.
Keywords: Bis thiazolidinone heterocycles, choline chloride, green chemistry, ionic liquids, multicomponent reactions, one-pot synthesis.
Letters in Organic Chemistry
Title:Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones
Volume: 10 Issue: 10
Author(s): Akbar Mobinikhaledi and Alireza Khajeh Amiri
Affiliation:
Keywords: Bis thiazolidinone heterocycles, choline chloride, green chemistry, ionic liquids, multicomponent reactions, one-pot synthesis.
Abstract: A high efficient and environmentally friendly procedure for the production of bis thiazolidinones has been developed. This synthetic approach involves the simple condensation of an appropriate dialdehyde and N,N'-diarylthioureas with chloroacetyl chloride in eutectic salts as a promoter and solvent at 80 °C. All products were obtained in good to excellent yields. Structures of these compounds were established on the basis of IR, 1H-NMR, 13C-NMR and by elemental analysis.
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Cite this article as:
Mobinikhaledi Akbar and Amiri Khajeh Alireza, Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones, Letters in Organic Chemistry 2013; 10 (10) . https://dx.doi.org/10.2174/157017861131000059
DOI https://dx.doi.org/10.2174/157017861131000059 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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