Abstract
In this article we present an update on the applications of chemiluminescence coupled with flow injection analysis for the determination of pharmaceuticals. Several reported applications of flow and sequential injection chemiluminescence (FI-CL/SI-CL) in pharmaceuticals concern greatly on quality control, investigation of dissolution of particular formulations or process control of production of pharmaceuticals and their presence in physiological fluids. A number of advances in the development of FI-CL methods have been reported in recent years on pharmaceutical analysis.
In the present review we have covered six years period from Jan-2007 to Dec-2012 discussing FI-CL/SI-CL in the liquid phase as an analytical tool for the determination of pharmaceuticals in diverse samples. We reviewed the methods as per general CL reaction involved with the help of 321 cited references. Interesting features of the FI-CL methods like the use of molecularly imprinting polymers for selectively and specially designed cells/microfluidic devices or lab-on-a-chip for better detection or sensitivity were also presented.
Keywords: Flow injection analysis, sequential injection, chemiluminescence, pharmaceuticals, biomedical applications, microfluidics.
Current Pharmaceutical Analysis
Title:Analytical Applications of Flow Injection Chemiluminescence for the Determination of Pharmaceuticals–A Review
Volume: 9 Issue: 4
Author(s): Amir Waseem, Mohammad Yaqoob and Abdul Nabi
Affiliation:
Keywords: Flow injection analysis, sequential injection, chemiluminescence, pharmaceuticals, biomedical applications, microfluidics.
Abstract: In this article we present an update on the applications of chemiluminescence coupled with flow injection analysis for the determination of pharmaceuticals. Several reported applications of flow and sequential injection chemiluminescence (FI-CL/SI-CL) in pharmaceuticals concern greatly on quality control, investigation of dissolution of particular formulations or process control of production of pharmaceuticals and their presence in physiological fluids. A number of advances in the development of FI-CL methods have been reported in recent years on pharmaceutical analysis.
In the present review we have covered six years period from Jan-2007 to Dec-2012 discussing FI-CL/SI-CL in the liquid phase as an analytical tool for the determination of pharmaceuticals in diverse samples. We reviewed the methods as per general CL reaction involved with the help of 321 cited references. Interesting features of the FI-CL methods like the use of molecularly imprinting polymers for selectively and specially designed cells/microfluidic devices or lab-on-a-chip for better detection or sensitivity were also presented.
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Cite this article as:
Waseem Amir, Yaqoob Mohammad and Nabi Abdul, Analytical Applications of Flow Injection Chemiluminescence for the Determination of Pharmaceuticals–A Review, Current Pharmaceutical Analysis 2013; 9 (4) . https://dx.doi.org/10.2174/15734129113099990002
DOI https://dx.doi.org/10.2174/15734129113099990002 |
Print ISSN 1573-4129 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-676X |
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