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Mini-Reviews in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-193X
ISSN (Online): 1875-6298

Application Progress of Recent Advances in Some Copper Catalyzed Coupling Reactions

Author(s): Sunil U. Tekale, Vivekanand B. Jadhav, Vijay P. Pagore, Sushma S. Kauthale, Digambar D. Gaikwad and Rajendra P. Pawar

Volume 10, Issue 3, 2013

Page: [281 - 301] Pages: 21

DOI: 10.2174/1570193X11310030007

Abstract

Different cross-coupling reactions for the formation of biologically important motifs and intermediates in organic synthesis using various suitable copper catalysts are reviewed. These include C-C, C-N, C-O, C-S heteroatom bond forming, cyclization and other miscellaneous reactions catalyzed by elemental copper, copper salts, CuI, Cu (OTf)2, CuBr, Cu2O etc. The use of copper reagents instead of palladium catalysts and ligands seems to be advantageous from the commercial point of view. The methods described herein afford the products in excellent yield without using expensive and moisture/air sensitive palladium catalysts, ligands and reagents.

Keywords: Copper catalysts, Cross coupling reactions, Ligands.


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