Generic placeholder image

Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Approaches to Virtual Screening and Screening Library Selection

Author(s): Scott A. Wildman

Volume 19, Issue 26, 2013

Page: [4787 - 4796] Pages: 10

DOI: 10.2174/1381612811319260009

Price: $65

Abstract

The ease of access to virtual screening (VS) software in recent years has resulted in a large increase in literature reports. Over 300 publications in the last year report the use of virtual screening techniques to identify new chemical matter or present the development of new virtual screening techniques. The increased use is accompanied by a corresponding increase in misuse and misinterpretation of virtual screening results. This review aims to identify many of the common difficulties associated with virtual screening and allow researchers to better assess the reliability of their virtual screening effort.

Keywords: Virtual screening, compound library, docking, scoring, QSAR, pharmacophore.

« Previous

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy