Abstract
Biologically active compounds with different modes of action, such as, antiproliferative, antioxidant, antimicrotubule, have been isolated from marine sources, specifically microalgae, cyanobacteria and seaweed. The structural characteristics of these peptides include various unusual amino acid residues, which may be responsible for their properties. Moreover, protein hydrolysates formed by the enzymatic digestion of aquatic and marine by-products are an important source of bioactive peptides.
Purified peptides from these sources have been shown to have antioxidant activity and cytotoxic effect on several human cancer cell lines such as HepG2, HeLa, AGS, and MCF-7. These characteristics imply that the use of peptides from marine sources has potential for the prevention and treatment of cancer, and that they might also be useful as molecular models in anticancer drug research.
This review focuses about the anticancer activating of peptides were prepared from microalgae in detail.
Keywords: Microalgae, anticancer, peptides.
Current Protein & Peptide Science
Title:Beneficial Effect of Peptides from Microalgae on Anticancer
Volume: 14 Issue: 3
Author(s): Kyong-Hwa Kang and Se-Kwon Kim
Affiliation:
Keywords: Microalgae, anticancer, peptides.
Abstract: Biologically active compounds with different modes of action, such as, antiproliferative, antioxidant, antimicrotubule, have been isolated from marine sources, specifically microalgae, cyanobacteria and seaweed. The structural characteristics of these peptides include various unusual amino acid residues, which may be responsible for their properties. Moreover, protein hydrolysates formed by the enzymatic digestion of aquatic and marine by-products are an important source of bioactive peptides.
Purified peptides from these sources have been shown to have antioxidant activity and cytotoxic effect on several human cancer cell lines such as HepG2, HeLa, AGS, and MCF-7. These characteristics imply that the use of peptides from marine sources has potential for the prevention and treatment of cancer, and that they might also be useful as molecular models in anticancer drug research.
This review focuses about the anticancer activating of peptides were prepared from microalgae in detail.
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Cite this article as:
Kang Kyong-Hwa and Kim Se-Kwon, Beneficial Effect of Peptides from Microalgae on Anticancer, Current Protein & Peptide Science 2013; 14 (3) . https://dx.doi.org/10.2174/1389203711314030009
DOI https://dx.doi.org/10.2174/1389203711314030009 |
Print ISSN 1389-2037 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5550 |
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