Clinical Cancer Drugs

Editor-in-Chief

Giulio Francia
The University of Texas
El Paso, TX
(USA)

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Open Access Articles

Clinical Impact of Gastric Acid Suppressants Use on the Efficacy of Gefitinib in Patients with Advanced Adenocarcinoma of the Lung Harboring Common EGFR Mutations open Access plus

Volume: 7   Issue: 1
Pp: 57-61
Wang Chun Kwok, James Chung Man Ho, David Chi Leung Lam, Macy Mei Sze Lui, Mary Sau Man Ip and Terence Chi Chun Tam*
DOI:10.2174/2212697X06666191021155535

Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways open Access plus

Volume: 7   Issue: 1
Pp: 44-56
Reena Kasi, Pei Ling Yeo, Ng. Khuen Yen, Rhun Yian Koh, Gnanajothy Ponnudurai, Yee Lian Tiong and Soi Moi Chye*
DOI:10.2174/2212697X06666191116151114

Complexity in Clinical Trials: Blind Spots, Misleading Criteria, Winners and Losers open Access plus

Volume: 7   Issue: 1
Pp: 3-15
Gang Yuan, Lishi Wang, Jing Li, Helin Feng, Jiafu Ji, Weikuan Gu* and Baoen Shan*
DOI:10.2174/2212697X06666191021125423

The Potential Role of Claudins in Regulation of Metastasis and Development of Drug Resistance in Breast Cancer open Access plus

Volume: 7   Issue: 1
Pp: 25-43
Hemantkumar Patadia, Ankita Priyadarshini, Jay Ranade and Ajit Gangawane*
DOI:10.2174/2212697X06666191021121022

Metformin Treatment Sensitizes Human Laryngeal Cancer Cell Line Hep- 2 to 5-Fluorouracil open Access plus

Volume: 7   Issue: 1
Pp: 16-24
Neslisah Barlak, Fatma Sanli, Ozel Capik, Elanur Tuysuz, Elanur Aydın Karatas, Hasan Turkez and Omer Faruk Karatas*
DOI:10.2174/2212697X06666190906165309

A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies open Access plus

Volume: 7  
Pp: 1-12
Karen A Gelmon*, Christian Kollmannsberger, Stephen Chia, Anna V. Tinker, Teresa Mitchell, Stephen Lam, Teresa Joshi, David Kwok, John Ostrem, Simon Sutcliffe and Daniel J Renouf
DOI:10.2174/1574893615999200601130946

Novel Molecular Targets and Mechanisms Involved in the Invasion and Metastasis of Pancreatic Cancer open Access plus

Volume: 6   Issue: 1
Pp: 8-20
Ziyi Li, Weidong Li, Yuqi Dong and Xueying Sun*
DOI:10.2174/2212697X06666190328180331

Head and Neck Cancer with Lung Metastases: Treatment Challenges open Access plus

Volume: 6   Issue: 1
Pp: 48-53
Selvamalar Vengathajalam* and Norhafiza Mat Lazim
DOI:10.2174/2212697X06666190701113911

Coenzyme Q10 Attenuates Cisplatin-induced Nephrotoxicity Through Counteracting Oxidative Stress and Inflammation open Access plus

Volume: 6   Issue: 1
Pp: 41-47
Hala S. Bash and Ihsan S. Rabeea*
DOI:10.2174/2212697X06666190701113043

A Marine-based Meriolin (3-Pyrimidinylazaindole) Derivative (4ab) Targets PI3K/AKT /mTOR Pathway Inducing Cell Cycle Arrest and Apoptosis in Molt-4 Cells open Access plus

Volume: 6   Issue: 1
Pp: 33-40
Gousia Chashoo*, Umed Singh, Parvinder P. Singh, Dilip M. Mondhe and Ram A. Vishwakarma
DOI:10.2174/2212697X06666190509094514

Targeting Breast Cancer Stem Cells (BCSCs) with Liposomal Formulations open Access plus

Volume: 6   Issue: 1
Pp: 3-7
Sumayah Al-Mahmood*
DOI:10.2174/2212697X06666190318150757

Evaluation of Fibrolytic Effect of Bauhinia purpurea L. open Access plus

Volume: 6   Issue: 1
Pp: 21-32
Jeevan R. Dash, Tapas K. Sar*, Rinku Buragohain, Indranil Samanta and Rahul Nanotkar
DOI:10.2174/2212697X06666190131155256

Computational Analysis of the Binding Site(s) of TNF β-TNFR1 Complex: Implications for Designing Novel Anticancer Agents open Access plus

Volume: 5   Issue: 2
Pp: 94-104
Trupti Kashinath Khatal and Ganesh Ulhasrao Chaturbhuj*
DOI:10.2174/2212697X06666181126111445

Erlotinib in Non-Small Cell Lung Cancer: From a thought to Necessity open Access plus

Volume: 5   Issue: 2
Pp: 87-93
Parijat Pandey and Harish Dureja*
DOI:10.2174/2212697X06666190102110412

May Endocrine Therapy be Associated with Cognitive Impairment in Breast Cancer Patients? open Access plus

Volume: 5   Issue: 2
Pp: 75-86
Riccardo Presciuttini, Romano Danesi and Guido Bocci*
DOI:10.2174/2212697X06666181219095936

New Robotic Technologies in Cancer Colon Screening open Access plus

Volume: 5   Issue: 2
Pp: 68-74
Luigi Manfredi* and Gianfranco Natale
DOI:10.2174/2212697X06666181220130020

Effects of Lysozyme on Ehrlich Ascites Carcinoma Cells: The Possible Physiological Role of Lysozyme in the Prevention of Carcinogenesis open Access plus

Volume: 5   Issue: 2
Pp: 113-118
Vardan K. Gasparyan*, Hayk A. Harutyunyan, Mariam V. Mikaelyan and Gayane G. Poghosyan
DOI:10.2174/2212697X06666190110120026

Formulation and Evaluation of pH Sensitive Sustained Release Hydrogel of Methotrexate open Access plus

Volume: 5   Issue: 2
Pp: 105-112
Swatantra Kumar Singh Kushwaha*, Prashant Kumar and Awani Kumar Rai
DOI:10.2174/2212697X06666190102105652

Novel Antibody Therapeutics Targeting Mesothelin In Solid Tumors open Access plus

Volume: 3   Issue: 2
Pp: 76-86
Xiao-Yan Zhao, Babu Subramanyam, Nenad Sarapa, Sven Golfier and Harald Dinter
DOI:10.2174/2212697X03666160218215744

Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors open Access plus

Volume: 3   Issue: 2
Pp: 131-137
G. Steven Martinez, Jeremy A. Ross and Robert A. Kirken
DOI:10.2174/2212697X03666160610085943

A Single Center Phase II Study of Continuous Infusion of Low-dose 5- fluorouracil for Heavily Pretreated Patients With Metastatic Colorectal Cancer open Access plus

Volume: 2   Issue: 2
Pp: 87-90
Hong-tao Chen, Yi-feng Liao, Mei Xiao, Lin Ma and Hong-Yu Zhang
DOI:10.2174/2212697X02666151026215656

The Importance of Lamivudine Therapy in Liver Cirrhosis Patients Related HBV with Advanced Hepatocellular Carcinoma Receiving Hepatic Arterial Infusion Chemotherapy open Access plus

Volume: 2   Issue: 2
Pp: 112-118
Koichi Momiyama, Hidenari Nagai, Yu Ogino, Takanori Mukouzu, Daigo Matsui, Michio Kogame, Teppei Matsui, Noritaka Wakui, Mie Shinohara, Yoshinori Igarashi and Yasukiyo Sumino
DOI:10.2174/2212697X02666150602220735

Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies open Access plus

Volume: 2   Issue: 2
Pp: 100-111
Benny Johnson and Daruka Mahadevan
DOI:10.2174/2212697X02666150602215823

Preclinical Models to Study Breast Cancer open Access plus

Volume: 1   Issue: 2
Pp: 90-99
Cynthia M. Rodriguez, Paloma Valenzuela, Natzidielly Lerma and Giulio Francia
DOI:10.2174/2212697X113026660005

Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy open Access plus

Volume: 1   Issue: 2
Pp: 116-126
Annabelle Chow, Giulio Francia, Andrew Kouri, Christina Lee, John M. Ebos, Robert S. Kerbel and Urban Emmenegger
DOI:10.2174/2212697X01666131218235200