Clinical Cancer Drugs

Editor-in-Chief

Giulio Francia
The University of Texas
El Paso, TX
(USA)

Personal Subscription
Become EABM
Become Reviewer

Open Access Articles

A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies open Access plus

Volume: 7   Issue: 2
Pp: 125-132
Karen A. Gelmon*, Christian Kollmannsberger, Stephen Chia, Anna V. Tinker, Teresa Mitchell, Stephen Lam, Teresa Joshi, David Kwok, John Ostrem, Simon Sutcliffe and Daniel J. Renouf
DOI:10.2174/1574893615999200601130946

The Association Between the Level of Leukemic Stem Cells and Treatment Response Among Chronic Myeloid Leukemia Patients Treated with Imatinib Mesylate open Access plus

Volume: 7   Issue: 2
Pp: 119-124
Shinta Oktya Wardhani*, Hani Susianti, Puji Rahayu and Yuyun Yueniwati
DOI:10.2174/2212697X07999200824115628

Clinical Impact of Gastric Acid Suppressants Use on the Efficacy of Gefitinib in Patients with Advanced Adenocarcinoma of the Lung Harboring Common EGFR Mutations open Access plus

Volume: 7   Issue: 1
Pp: 57-61
Wang Chun Kwok, James Chung Man Ho, David Chi Leung Lam, Macy Mei Sze Lui, Mary Sau Man Ip and Terence Chi Chun Tam*
DOI:10.2174/2212697X06666191021155535

Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways open Access plus

Volume: 7   Issue: 1
Pp: 44-56
Reena Kasi, Pei Ling Yeo, Ng. Khuen Yen, Rhun Yian Koh, Gnanajothy Ponnudurai, Yee Lian Tiong and Soi Moi Chye*
DOI:10.2174/2212697X06666191116151114

Complexity in Clinical Trials: Blind Spots, Misleading Criteria, Winners and Losers open Access plus

Volume: 7   Issue: 1
Pp: 3-15
Gang Yuan, Lishi Wang, Jing Li, Helin Feng, Jiafu Ji, Weikuan Gu* and Baoen Shan*
DOI:10.2174/2212697X06666191021125423

The Potential Role of Claudins in Regulation of Metastasis and Development of Drug Resistance in Breast Cancer open Access plus

Volume: 7   Issue: 1
Pp: 25-43
Hemantkumar Patadia, Ankita Priyadarshini, Jay Ranade and Ajit Gangawane*
DOI:10.2174/2212697X06666191021121022

Metformin Treatment Sensitizes Human Laryngeal Cancer Cell Line Hep- 2 to 5-Fluorouracil open Access plus

Volume: 7   Issue: 1
Pp: 16-24
Neslisah Barlak, Fatma Sanli, Ozel Capik, Elanur Tuysuz, Elanur Aydın Karatas, Hasan Turkez and Omer Faruk Karatas*
DOI:10.2174/2212697X06666190906165309

Novel Molecular Targets and Mechanisms Involved in the Invasion and Metastasis of Pancreatic Cancer open Access plus

Volume: 6   Issue: 1
Pp: 8-20
Ziyi Li, Weidong Li, Yuqi Dong and Xueying Sun*
DOI:10.2174/2212697X06666190328180331

Head and Neck Cancer with Lung Metastases: Treatment Challenges open Access plus

Volume: 6   Issue: 1
Pp: 48-53
Selvamalar Vengathajalam* and Norhafiza Mat Lazim
DOI:10.2174/2212697X06666190701113911

Coenzyme Q10 Attenuates Cisplatin-induced Nephrotoxicity Through Counteracting Oxidative Stress and Inflammation open Access plus

Volume: 6   Issue: 1
Pp: 41-47
Hala S. Bash and Ihsan S. Rabeea*
DOI:10.2174/2212697X06666190701113043

A Marine-based Meriolin (3-Pyrimidinylazaindole) Derivative (4ab) Targets PI3K/AKT /mTOR Pathway Inducing Cell Cycle Arrest and Apoptosis in Molt-4 Cells open Access plus

Volume: 6   Issue: 1
Pp: 33-40
Gousia Chashoo*, Umed Singh, Parvinder P. Singh, Dilip M. Mondhe and Ram A. Vishwakarma
DOI:10.2174/2212697X06666190509094514

Targeting Breast Cancer Stem Cells (BCSCs) with Liposomal Formulations open Access plus

Volume: 6   Issue: 1
Pp: 3-7
Sumayah Al-Mahmood*
DOI:10.2174/2212697X06666190318150757

Evaluation of Fibrolytic Effect of Bauhinia purpurea L. open Access plus

Volume: 6   Issue: 1
Pp: 21-32
Jeevan R. Dash, Tapas K. Sar*, Rinku Buragohain, Indranil Samanta and Rahul Nanotkar
DOI:10.2174/2212697X06666190131155256

Computational Analysis of the Binding Site(s) of TNF β-TNFR1 Complex: Implications for Designing Novel Anticancer Agents open Access plus

Volume: 5   Issue: 2
Pp: 94-104
Trupti Kashinath Khatal and Ganesh Ulhasrao Chaturbhuj*
DOI:10.2174/2212697X06666181126111445

Erlotinib in Non-Small Cell Lung Cancer: From a thought to Necessity open Access plus

Volume: 5   Issue: 2
Pp: 87-93
Parijat Pandey and Harish Dureja*
DOI:10.2174/2212697X06666190102110412

May Endocrine Therapy be Associated with Cognitive Impairment in Breast Cancer Patients? open Access plus

Volume: 5   Issue: 2
Pp: 75-86
Riccardo Presciuttini, Romano Danesi and Guido Bocci*
DOI:10.2174/2212697X06666181219095936

New Robotic Technologies in Cancer Colon Screening open Access plus

Volume: 5   Issue: 2
Pp: 68-74
Luigi Manfredi* and Gianfranco Natale
DOI:10.2174/2212697X06666181220130020

Effects of Lysozyme on Ehrlich Ascites Carcinoma Cells: The Possible Physiological Role of Lysozyme in the Prevention of Carcinogenesis open Access plus

Volume: 5   Issue: 2
Pp: 113-118
Vardan K. Gasparyan*, Hayk A. Harutyunyan, Mariam V. Mikaelyan and Gayane G. Poghosyan
DOI:10.2174/2212697X06666190110120026

Formulation and Evaluation of pH Sensitive Sustained Release Hydrogel of Methotrexate open Access plus

Volume: 5   Issue: 2
Pp: 105-112
Swatantra Kumar Singh Kushwaha*, Prashant Kumar and Awani Kumar Rai
DOI:10.2174/2212697X06666190102105652

Novel Antibody Therapeutics Targeting Mesothelin In Solid Tumors open Access plus

Volume: 3   Issue: 2
Pp: 76-86
Xiao-Yan Zhao, Babu Subramanyam, Nenad Sarapa, Sven Golfier and Harald Dinter
DOI:10.2174/2212697X03666160218215744

Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors open Access plus

Volume: 3   Issue: 2
Pp: 131-137
G. Steven Martinez, Jeremy A. Ross and Robert A. Kirken
DOI:10.2174/2212697X03666160610085943

A Single Center Phase II Study of Continuous Infusion of Low-dose 5- fluorouracil for Heavily Pretreated Patients With Metastatic Colorectal Cancer open Access plus

Volume: 2   Issue: 2
Pp: 87-90
Hong-tao Chen, Yi-feng Liao, Mei Xiao, Lin Ma and Hong-Yu Zhang
DOI:10.2174/2212697X02666151026215656

The Importance of Lamivudine Therapy in Liver Cirrhosis Patients Related HBV with Advanced Hepatocellular Carcinoma Receiving Hepatic Arterial Infusion Chemotherapy open Access plus

Volume: 2   Issue: 2
Pp: 112-118
Koichi Momiyama, Hidenari Nagai, Yu Ogino, Takanori Mukouzu, Daigo Matsui, Michio Kogame, Teppei Matsui, Noritaka Wakui, Mie Shinohara, Yoshinori Igarashi and Yasukiyo Sumino
DOI:10.2174/2212697X02666150602220735

Emerging Role and Targeting of Carcinoembryonic Antigen-related Cell Adhesion Molecule 6 (CEACAM6) in Human Malignancies open Access plus

Volume: 2   Issue: 2
Pp: 100-111
Benny Johnson and Daruka Mahadevan
DOI:10.2174/2212697X02666150602215823

Preclinical Models to Study Breast Cancer open Access plus

Volume: 1   Issue: 2
Pp: 90-99
Cynthia M. Rodriguez, Paloma Valenzuela, Natzidielly Lerma and Giulio Francia
DOI:10.2174/2212697X113026660005

Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy open Access plus

Volume: 1   Issue: 2
Pp: 116-126
Annabelle Chow, Giulio Francia, Andrew Kouri, Christina Lee, John M. Ebos, Robert S. Kerbel and Urban Emmenegger
DOI:10.2174/2212697X01666131218235200