A Simple Access in One Step to Some New Substituted Pyrazolo- and [1,2,4]triazolo-[1,5-a]pyrimidines

Title:A Simple Access in One Step to Some New Substituted Pyrazolo- and [1,2,4]triazolo-[1,5-a]pyrimidines

Volume: 10 Issue: 2

Author(s): Monaem Balti, Khaireddine Dridi and Mohamed Lotfi El Efrit

Affiliation:

Keywords: β-cyanohydrazines, ketene dithioketals, pyrazolopyrimidines, triazolopyrimidines

Abstract: A convenient method was established for the synthesis of some new 6,7-dihydro-2-(methylthio)-5- aminopyrazolo[1,5-a]pyrimidine-3-carbonitriles 4 and -[1,2,4]triazolo[1,5-a]pyrimidin-5-amines 5 from β- cyanohydrazines 3 and suitable ketene dithioketals 2-[bis(methylthio)methylene]propanedinitrile 1 and dimethyl Ncyanocarbonimidodithioate 2, respectively in good yields. The structure of the title compound was characterized by IR, EA, ¹H- and ¹³C-NMR.

Cite this article as:

Balti Monaem, Dridi Khaireddine and Lotfi El Efrit Mohamed, A Simple Access in One Step to Some New Substituted Pyrazolo- and [1,2,4]triazolo-[1,5-a]pyrimidines, Letters in Organic Chemistry 2013; 10 (2) . https://dx.doi.org/10.2174/1570178611310020009