Abstract
Present-day is developing in many fields. Many pathological processes are better understood, including carcinogenesis. Consequently, the failure of pharmacotherapy aimed at cancerous diseases is becoming explainable. At the same time, new anticancer drugs continue to be introduced. Anthracycline antibiotics are a well-known and widely used group of anticancer drugs. However, in addition to their efficiency they demonstrate severe side effects compounded by the appearance of resistant cells. Therefore, the search for new anthracycline derivatives with improved pharmacodynamic properties and fewer adverse effects is in progress, delivering promising results.
Keywords: Anthracycline antibiotics, drugs modifications, cancer, cardiotoxicity
Mini-Reviews in Medicinal Chemistry
Title:Anthracyclines Still Prove Effective in Anticancer Therapy
Volume: 13 Issue: 5
Author(s): Mikolaj Piekarski and Anna Jelinska
Affiliation:
Keywords: Anthracycline antibiotics, drugs modifications, cancer, cardiotoxicity
Abstract: Present-day is developing in many fields. Many pathological processes are better understood, including carcinogenesis. Consequently, the failure of pharmacotherapy aimed at cancerous diseases is becoming explainable. At the same time, new anticancer drugs continue to be introduced. Anthracycline antibiotics are a well-known and widely used group of anticancer drugs. However, in addition to their efficiency they demonstrate severe side effects compounded by the appearance of resistant cells. Therefore, the search for new anthracycline derivatives with improved pharmacodynamic properties and fewer adverse effects is in progress, delivering promising results.
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Cite this article as:
Piekarski Mikolaj and Jelinska Anna, Anthracyclines Still Prove Effective in Anticancer Therapy, Mini-Reviews in Medicinal Chemistry 2013; 13 (5) . https://dx.doi.org/10.2174/1389557511313050001
DOI https://dx.doi.org/10.2174/1389557511313050001 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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