Abstract
Aldehydes were respectively converted to the corresponding 2-imidazolines in good yields by the reaction with ethylenediamine using iron (III) phosphate on water under reflux condition. Furthermore nitriles were converted to the corresponding 2-imidazolines under solvent-free condition at 100 °C. Utilizing of heterogeneous and recyclable catalyst, water as a solvent and solvent-free condition is the best medium from a green chemistry standpoint.
Keywords: Green chemistry, Iron (III) phosphate, Imidazoline, Solvent-free, Water mediated, Reusability of the Catalyst, Iron (III) phosphate, Antihypertensive, Antialzimer, Antitumor
Current Organic Chemistry
Title:Solvent-free and Water Mediated Synthesis of 2-Substituted Imidazolines Using Iron (III) Phosphate
Volume: 17 Issue: 3
Author(s): Farahnaz K. Behbahani, Toktam Sheibani Daloee and Parisa Ziaei
Affiliation:
Keywords: Green chemistry, Iron (III) phosphate, Imidazoline, Solvent-free, Water mediated, Reusability of the Catalyst, Iron (III) phosphate, Antihypertensive, Antialzimer, Antitumor
Abstract: Aldehydes were respectively converted to the corresponding 2-imidazolines in good yields by the reaction with ethylenediamine using iron (III) phosphate on water under reflux condition. Furthermore nitriles were converted to the corresponding 2-imidazolines under solvent-free condition at 100 °C. Utilizing of heterogeneous and recyclable catalyst, water as a solvent and solvent-free condition is the best medium from a green chemistry standpoint.
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Cite this article as:
K. Behbahani Farahnaz, Sheibani Daloee Toktam and Ziaei Parisa, Solvent-free and Water Mediated Synthesis of 2-Substituted Imidazolines Using Iron (III) Phosphate, Current Organic Chemistry 2013; 17 (3) . https://dx.doi.org/10.2174/1385272811317030010
DOI https://dx.doi.org/10.2174/1385272811317030010 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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