Rhodium-Catalyzed Hydroformylation Promoted by Modified Cyclodextrins: Current Scope and Future Developments

Author(s): Frédéric Hapiot, Loïc Leclercq, Nathalie Azaroual, Sophie Fourmentin, Sébastien Tilloy and Eric Monflier

Pp: 36-63 (28)

* (Excluding Mailing and Handling)

Abstract

The contribution of modified cyclodextrins in aqueous biphasic rhodiumcatalyzed hydroformylation of higher olefins is tackled, taking into account previous results and new experimental data. The role of the cyclodextrins is emphasized and discussed through the analysis of numerous parameters. Development outlooks are also presented.

Keywords: Hydroformylation, olefin, aldehyde, rhodium, water soluble phosphine, water soluble ligand, amphiphilic ligand, biphasic catalysis, phase transfer catalysis, interfacial catalysis, thermoregulated catalysis, catalyst recycling, mass transfer, micelle, cyclodextrin, host guest chemistry, inclusion complex, supramolecular adduct, High Pressure NMR spectroscopy, 1H Diffusion-Ordered NMR spectroscopy, surface tension, molecular dynamics.