Abstract
Infection with Human Immunodeficiency Virus (HIV) remains a global public health problem. Although the epidemic has not been completely controlled, there was considerable progress in HIV prevention and treatment during the last 30 years. The modern prevention approaches are multi-component including also the administration of combinations of potent antiretroviral agents as a prophylaxis after occupational or non-occupational exposures to HIV. The aim of the current review is to present the chemical and pharmacological characteristics of antiretroviral drugs used in HIV prophylaxis and to describe briefly the medical management of exposures to potentially infectious body fluids.
Keywords: HIV, prophylaxis, antiretrovirals, exposure, occupational, non-occupational
Current Medicinal Chemistry
Title:Antiretrovirals for HIV Exposure Prophylaxis
Volume: 19 Issue: 35
Author(s): G. Nikolopoulos, S. Tsiodras, S. Bonovas and A. Hatzakis
Affiliation:
Keywords: HIV, prophylaxis, antiretrovirals, exposure, occupational, non-occupational
Abstract: Infection with Human Immunodeficiency Virus (HIV) remains a global public health problem. Although the epidemic has not been completely controlled, there was considerable progress in HIV prevention and treatment during the last 30 years. The modern prevention approaches are multi-component including also the administration of combinations of potent antiretroviral agents as a prophylaxis after occupational or non-occupational exposures to HIV. The aim of the current review is to present the chemical and pharmacological characteristics of antiretroviral drugs used in HIV prophylaxis and to describe briefly the medical management of exposures to potentially infectious body fluids.
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Cite this article as:
Nikolopoulos G., Tsiodras S., Bonovas S. and Hatzakis A., Antiretrovirals for HIV Exposure Prophylaxis, Current Medicinal Chemistry 2012; 19 (35) . https://dx.doi.org/10.2174/0929867311209065924
DOI https://dx.doi.org/10.2174/0929867311209065924 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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