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Recent Patents on Biomedical Engineering (Discontinued)

Editor-in-Chief

ISSN (Print): 2211-3320
ISSN (Online): 1874-7647

Materials for Articular Cartilage Regeneration

Author(s): Aysegul Tombuloglu, Ayse B. Tekinay and Mustafa O. Guler

Volume 5, Issue 3, 2012

Page: [187 - 199] Pages: 13

DOI: 10.2174/1874764711205030187

Price: $65

Abstract

Many health problems remaining to be untreatable throughout the human history can be overcome by utilizing new biomedical materials. Healing cartilage defects is one of the problems causing significant health issue due to low regeneration capacity of the cartilage tissue. Scaffolds as three-dimensional functional networks provide promising tools for complete regeneration of the cartilage tissue. Diversity of materials and fabrication methods give rise to many forms of scaffolds including injectable and mechanically stable ones. Various approaches can be considered depending on the condition of cartilage defect. A scaffold should maintain tissue function within a short time, and should be easily applied in order to minimally harm the body. This review will cover several patents and other publications on materials for cartilage regeneration with an outlook on essential characteristics of materials and scaffolds.

Keywords: Cartilage, Regenerative Medicine, Biomaterials, Scaffold, peptide, Polymer.

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