Abstract
A green and efficient synthesis of novel 4-thiazolidinones 4 from cyclocondensation reaction of 2-(2,3-dihydro- 1H-carbazol-4(9H)-ylidene)hydrazinecarbothioamide 3 and α-haloacids catalyzed by N-methylpyridinium tosylate in quantitative yield is reported. Also, synthesis of new 2,4-disubstituted thiazoles 5 under grinding conditions is reported.
Keywords: 4-Thiazolidinones, N-methylpyridinium tosylate, cyclocondensation, thiazoles, grinding, heterocyclic carbazole motif, optoelectronic devices, quantitative, internal standard, chromatography
Letters in Organic Chemistry
Title:Expedient and Green Synthesis of Some Novel 4-Thiazolidinones and New 2,4-Disubstituted Thiazoles with Tetrahydro Carbazole Pendant
Volume: 9 Issue: 9
Author(s): Deepika Gautam, Poonam Gautam and Ram P. Chaudhary
Affiliation:
Keywords: 4-Thiazolidinones, N-methylpyridinium tosylate, cyclocondensation, thiazoles, grinding, heterocyclic carbazole motif, optoelectronic devices, quantitative, internal standard, chromatography
Abstract: A green and efficient synthesis of novel 4-thiazolidinones 4 from cyclocondensation reaction of 2-(2,3-dihydro- 1H-carbazol-4(9H)-ylidene)hydrazinecarbothioamide 3 and α-haloacids catalyzed by N-methylpyridinium tosylate in quantitative yield is reported. Also, synthesis of new 2,4-disubstituted thiazoles 5 under grinding conditions is reported.
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Cite this article as:
Gautam Deepika, Gautam Poonam and P. Chaudhary Ram, Expedient and Green Synthesis of Some Novel 4-Thiazolidinones and New 2,4-Disubstituted Thiazoles with Tetrahydro Carbazole Pendant, Letters in Organic Chemistry 2012; 9 (9) . https://dx.doi.org/10.2174/157017812803521081
DOI https://dx.doi.org/10.2174/157017812803521081 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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