Polymeric Nanoparticles of FMISO: Are Nano-Radiopharmaceuticals Better Than Conventional Ones?

Title:Polymeric Nanoparticles of FMISO: Are Nano-Radiopharmaceuticals Better Than Conventional Ones?

Volume: 5 Issue: 4

Author(s): Marta de Souza Albernaz, Beatriz Ferreira de Carvalho Patricio, Gilberto Weissmuller, Franceline Reynaud, Tom CH Adamsen and Ralph Santos-Oliveira

Affiliation:

Keywords: Radiopharmaceuticals, Oncology, Nuclear Medicine, Hypoxia, Predictive.

Abstract: Nanotechnology has been the last frontier in the diagnoses and treatment of many diseases, especially in oncology. The use of nanoparticles of radiopharmaceuticals may represent the future of Nuclear Medicine. In this study we developed, characterized and tested polymeric nanoparticles of FMISO (fluoromisonidazole) in a dynamic study of biodistribution. The results of the development as characterization showed that nanoparticles were well obtained with a size range of 300- 500nm and a spherical shape.

Cite this article as:

de Souza Albernaz Marta, Ferreira de Carvalho Patricio Beatriz, Weissmuller Gilberto, Reynaud Franceline, CH Adamsen Tom and Santos-Oliveira Ralph, Polymeric Nanoparticles of FMISO: Are Nano-Radiopharmaceuticals Better Than Conventional Ones?, Current Radiopharmaceuticals 2012; 5 (4) . https://dx.doi.org/10.2174/1874471011205040336