Abstract
Electrochemical biosensing, due to its sensitivity and specificity, combined with the low-cost and operation convenience of the equipment, is considered as a promising point-of-care approach in clinical analysis. This review presents the basic principles of operation, the current status, and the trends in the development and the clinical implementation of some selected electrochemical biosensors. These include: electrochemical glucose biosensors successfully applied in diabetes management, and electrochemical biosensors for cholinesterases and trypsin activities determination. The latter, although less common, demonstrate the potential of improving the existing clinical methods in the diagnostics and the treatment of neurotoxic, neurological, and pancreatic diseases.
Keywords: Biosensors, clinical analysis, cholinesterases, glucose, trypsin.
Mini-Reviews in Medicinal Chemistry
Title:Some clinical applications of the electrochemical biosensors
Volume: 12 Issue: 12
Author(s): Michelle Arredondo, Margarita Stoytcheva, Roumen Zlatev and Velizar Gochev
Affiliation:
Keywords: Biosensors, clinical analysis, cholinesterases, glucose, trypsin.
Abstract: Electrochemical biosensing, due to its sensitivity and specificity, combined with the low-cost and operation convenience of the equipment, is considered as a promising point-of-care approach in clinical analysis. This review presents the basic principles of operation, the current status, and the trends in the development and the clinical implementation of some selected electrochemical biosensors. These include: electrochemical glucose biosensors successfully applied in diabetes management, and electrochemical biosensors for cholinesterases and trypsin activities determination. The latter, although less common, demonstrate the potential of improving the existing clinical methods in the diagnostics and the treatment of neurotoxic, neurological, and pancreatic diseases.
Export Options
About this article
Cite this article as:
Arredondo Michelle, Stoytcheva Margarita, Zlatev Roumen and Gochev Velizar, Some clinical applications of the electrochemical biosensors, Mini-Reviews in Medicinal Chemistry 2012; 12 (12) . https://dx.doi.org/10.2174/138955712802762031
DOI https://dx.doi.org/10.2174/138955712802762031 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Neuroleptic Malignant Syndrome: A Review from a Clinically Oriented Perspective
Current Neuropharmacology Cardioprotective Effects of the I<sub>f</sub> Current Inhibition by Ivabradine During Cardiac Dysfunction
Current Pharmaceutical Biotechnology Characterization and Antihypertensive Effect of the Complex of (-)-β- pinene in β-cyclodextrin
Current Pharmaceutical Biotechnology Inflammatory Caspases: Targets for Novel Therapies
Current Pharmaceutical Design Prevention and Management of Ovarian Hyperstimulation Syndrome
Current Women`s Health Reviews Cardiovascular Alterations After Spinal Cord Injury: An Overview
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Mechanisms and Medical Management of Exercise Intolerance in Hypertrophic Cardiomyopathy
Current Pharmaceutical Design Potential Biomarkers in Diabetic Retinopathy
Current Diabetes Reviews Current Metabolomic Methodologies & their Application to Thermal Stress
Current Metabolomics Reliability of Blood Pressure Patterns Defined by a Single 24-Hour Ambulatory Blood Pressure Monitoring: The Case of the Dipping/Non Dipping and Isolated Clinic Hypertension
Current Hypertension Reviews Low Doses of G-CSF Prevent Cerebral Infarction and Maintain Muscle Strength in an Experimental Model of Global Ischemic Stroke
Current Pharmaceutical Biotechnology Pharmacological and Biological Activities of Xanthones
Anti-Infective Agents in Medicinal Chemistry Sulfaphenazole and α-Naphthoflavone Attenuate the Metabolism of the Synthetic Cannabinoids JWH-018 and AM2201 Found in K2/Spice
Drug Metabolism Letters Magnesium and Anaesthesia
Current Drug Targets Single-dose Pharmacokinetics and Tolerability of Oral Delta-9- Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis
Drug Metabolism Letters Fluoroquinolones, the Cornerstone of Treatment of Drug-Resistant Tuberculosis: A Pharmacokinetic and Pharmacodynamic Approach
Current Pharmaceutical Design Beta-Blockers in the Treatment of Dilated Cardiomyopathy: Which is the Best?
Current Pharmaceutical Design Nutrition and Physical Activity on Hypertension: Implication of Current Evidence and Guidelines
Current Hypertension Reviews The Updated Role of the Blood Brain Barrier in Subarachnoid Hemorrhage: From Basic and Clinical Studies
Current Neuropharmacology Safety and Efficacy of Melatonin in Pediatric Migraine Prophylaxis
Current Drug Safety