Abstract
The genus of Forsythia (Oleaceae), composing ca. 10~15 species, is mostly native to eastern Asia and used in oriental traditional medicines. Phytochemical investigations on Forsythia species have shown that triterpenoids, lignans, flavonoids, phenylethanoid glycosides and C6-C2 natural alcohols, accumulated mainly in the fruits, are the major components. Many studies have elucidated that phenolic compounds, including lignans, phenylethanoid glycosides and flavonoids are responsible for the various biological activities of the herbal medicine. This review lists 141 chemical constituents as well as their biosynthetic pathway, bioactivities and quality control as reported until September, 2011 (104 references).
Keywords: Forsythia, chemical constituents, lignans, phenylethanoid glycosides, C6-C2 natural alcohols, biosynthesis, bioactivities, quality control.
Mini-Reviews in Organic Chemistry
Title:Chemical Constituents of Plants from the Genus Forsythia
Volume: 9 Issue: 3
Author(s): Qing Zhang, Chenhong Jia, Haiyun Xu, Yufang Wang, Manli Zhang, Changhong Huo, Qingwen Shi and Shuhong Yu
Affiliation:
Keywords: Forsythia, chemical constituents, lignans, phenylethanoid glycosides, C6-C2 natural alcohols, biosynthesis, bioactivities, quality control.
Abstract: The genus of Forsythia (Oleaceae), composing ca. 10~15 species, is mostly native to eastern Asia and used in oriental traditional medicines. Phytochemical investigations on Forsythia species have shown that triterpenoids, lignans, flavonoids, phenylethanoid glycosides and C6-C2 natural alcohols, accumulated mainly in the fruits, are the major components. Many studies have elucidated that phenolic compounds, including lignans, phenylethanoid glycosides and flavonoids are responsible for the various biological activities of the herbal medicine. This review lists 141 chemical constituents as well as their biosynthetic pathway, bioactivities and quality control as reported until September, 2011 (104 references).
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Zhang Qing, Jia Chenhong, Xu Haiyun, Wang Yufang, Zhang Manli, Huo Changhong, Shi Qingwen and Yu Shuhong, Chemical Constituents of Plants from the Genus Forsythia, Mini-Reviews in Organic Chemistry 2012; 9 (3) . https://dx.doi.org/10.2174/1570193X11209030303
DOI https://dx.doi.org/10.2174/1570193X11209030303 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
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