Abstract
Rapidly developing pulmonary fibrosis associated with the use of the anti-cancer drug oxaliplatin has been reported mainly by Asiatic literature as isolate case reports. This rare but potentially fatal side effect has neither identified risk factors nor established treatment guideline. We report here a new clinical case concerning a patient with advanced gastric cancer treated with the oxaliplatin-based FOLFOX regimen along with a review of the literature as well as a discussion of emerging experimental treatment mainly based on imatinib.
Keywords: Imatinib, oxaliplatin, pulmonary fibrosis.
Current Drug Safety
Title:Oxaliplatin-Induced Lung Toxicity. Case Report and Review of the Literature
Volume: 7 Issue: 2
Author(s): Tiziana Prochilo, Chiara Abeni, Paola Bertocchi and Alberto Zaniboni
Affiliation:
Keywords: Imatinib, oxaliplatin, pulmonary fibrosis.
Abstract: Rapidly developing pulmonary fibrosis associated with the use of the anti-cancer drug oxaliplatin has been reported mainly by Asiatic literature as isolate case reports. This rare but potentially fatal side effect has neither identified risk factors nor established treatment guideline. We report here a new clinical case concerning a patient with advanced gastric cancer treated with the oxaliplatin-based FOLFOX regimen along with a review of the literature as well as a discussion of emerging experimental treatment mainly based on imatinib.
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Cite this article as:
Prochilo Tiziana, Abeni Chiara, Bertocchi Paola and Zaniboni Alberto, Oxaliplatin-Induced Lung Toxicity. Case Report and Review of the Literature, Current Drug Safety 2012; 7 (2) . https://dx.doi.org/10.2174/157488612802715672
DOI https://dx.doi.org/10.2174/157488612802715672 |
Print ISSN 1574-8863 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3911 |
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