Abstract
Descending necrotizing mediastinitis is an acute, polymicrobial infection. Originating in the pharynx or neck, this necrotizing process descends into the chest producing widespread tissue necrosis. Despite the introduction of modern antimicrobial therapy and computed tomographic imaging, this form of mediastinitis has continued to produce reported mortality rates of 25% to 40%. This review discusses the pathophysiology, diagnosis and treatment of descending necrotizing mediastinitis with recommendations for treating physicians based on the modern literature.
Keywords: Descending, mediastinitis, necrotizing, polymicrobial infection, tissue necrosis, PATHOPHYSIOLOGY, cervicofascial infection, computed tomographic imaging, chest roentgenograms, modern.
Current Respiratory Medicine Reviews
Title:Descending Necrotizing Mediastinitis: Current Strategies for Diagnosis and Treatment
Volume: 8 Issue: 4
Author(s): Richard K. Freeman, Theresa Giannini, Amy Vyverberg and Anthony J. Ascioti
Affiliation:
Keywords: Descending, mediastinitis, necrotizing, polymicrobial infection, tissue necrosis, PATHOPHYSIOLOGY, cervicofascial infection, computed tomographic imaging, chest roentgenograms, modern.
Abstract: Descending necrotizing mediastinitis is an acute, polymicrobial infection. Originating in the pharynx or neck, this necrotizing process descends into the chest producing widespread tissue necrosis. Despite the introduction of modern antimicrobial therapy and computed tomographic imaging, this form of mediastinitis has continued to produce reported mortality rates of 25% to 40%. This review discusses the pathophysiology, diagnosis and treatment of descending necrotizing mediastinitis with recommendations for treating physicians based on the modern literature.
Export Options
About this article
Cite this article as:
K. Freeman Richard, Giannini Theresa, Vyverberg Amy and J. Ascioti Anthony, Descending Necrotizing Mediastinitis: Current Strategies for Diagnosis and Treatment, Current Respiratory Medicine Reviews 2012; 8 (4) . https://dx.doi.org/10.2174/157339812802652224
DOI https://dx.doi.org/10.2174/157339812802652224 |
Print ISSN 1573-398X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6387 |
Call for Papers in Thematic Issues
Exposure to PM2.5 components is associated with respiratory diseases
Through continuous research on the relationship between risk factors and health, it has been found that air pollution, especially atmospheric particulate matter pollution, has become one of the main sources of global disease burden. From 1990 to 2022, the concentration of atmospheric particulate matter pollution has increased by more than ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Are Some Anticoagulants More Equal Than Others? - Evaluating the Role of Novel Oral Anticoagulants in AF Ablation
Current Cardiology Reviews Deep Inspiration Breath-hold (DIBH) Technique to Reduce Cardiac Radiation Dose in the Management of Breast Cancer
Current Cancer Therapy Reviews Cardiovascular Manifestations of COVID-19
Current Cardiology Reviews Pathophysiology of Myocardial Infarction and Acute Management Strategies
Cardiovascular & Hematological Agents in Medicinal Chemistry COMPLICATIONS OF RECANALIZATION OF CHRONIC TOTAL OCCLUSION
Current Cardiology Reviews Cardiac Amyloid - A Hidden Contributor to Cardiac Dysfunction Following Cardiac Surgery: Case Report and Literature Review
Current Cardiology Reviews Pharmacological Therapy of Pericardial Diseases
Current Pharmaceutical Design Management of Massive Obstetric Haemorrhage
Current Women`s Health Reviews Management of Hypertension in the Acute Phase of Stroke
Current Hypertension Reviews Microvascular Obstruction After Primary Percutaneous Coronary Intervention: Pathogenesis, Diagnosis and Prognostic Significance
Current Vascular Pharmacology Collateral Circulation in Chronic Total Occlusions – an interventional perspective
Current Cardiology Reviews Mitral Balloon Valvuloplasty: State-of-the-Art Paper
Current Cardiology Reviews The LIM Protein fhlA is Essential for Heart Chamber Development in Zebrafish Embryos
Current Molecular Medicine Complications in Patients with Cardiac Penetrating Trauma
Cardiovascular & Hematological Disorders-Drug Targets Clinical Management of the Cardiovascular Failure in Sepsis
Current Vascular Pharmacology Access-site Complications of the Transradial Approach: Rare But Still There
Current Cardiology Reviews Postoperative Care of the Transplanted Patient
Current Cardiology Reviews A Review of Cardiogenic Shock in Acute Myocardial Infarction
Current Cardiology Reviews Spontaneous Biliary Pericardial Tamponade: A Case Report and Literature Review
Current Cardiology Reviews Thoracic Surgical Approaches in the Trauma Setting: A Basic Review
Current Respiratory Medicine Reviews