Current Metabolomics

(Continued as Current Metabolomics and Systems Biology)

ISSN (Print): 2213-235X
ISSN (Online): 2213-2368

Volume 6, Issues 3, 2018

Editorial Board

cmb Co-Editor-in-Chief cmb_ebm_powers_001 Powers Robert University of Nebraska-Lincoln Lincoln NE USA

Dr. Robert Powers is currently a Professor of Chemistry at the University of Nebraska-Lincoln. He has more than 30 years of experience in NMR spectroscopy, structural biology, metabolomics, and drug discovery. He received his BA from Rutgers University, a Ph.D. in chemistry fromt Purdue University, and was a postdoctoral fellow at the NIH laboratory of Chemical Physics. Prior to arriving at UNL, Dr. Powers was an Associate Director for the Protein NMR group at Wyeth. Dr. Powers is the Editor-in-Chief of Current Metabolomics and has written over 120 peer-reviewed manuscripts, 5 book chapters, and is an inventor on 9 patents.

cmb_ebm_watson_001 Watson David Strathclyde Institute of Pharmacy and Biomedical Sciences Glasgow UK

Dave Watson BSc PhD PGCE is a reader in Pharmaceutical Sciences at the University of Strathclyde up He has specialised in chromatographic methods combined with mass spectrometry which he has applied to a range of problems ranging from drug metabolism and disposition through to metabolomics. He published a popular undergraduate textbook on Pharmaceutical Analysis textbook on Pharmaceutical Chemistry. He has been first supervisor for 45 completed PhD students and currently has a group of 18 PhD students. He has published 280 papers and reviews. He was local organiser and chair of the 2013 Metabolomics Conference which was held in Glasgow. Current interests include: mass spectrometric metabolomics in Crohn’s disease, metal toxicity, metabolic syndrome, exercise and immunology.

Associate Editors cmb_ebm_porter_001 Assadi-Porter F. University of Wisconsin-Madison Madison WI USA

Dr. Fariba Assadi-Porter is Senior Scientist and Principal Investigator in the Department of Zoology at the University of Wisconsin-Madison with over 20 years of research in biochemistry, NMR spectroscopy, and metabolism studies. She obtained her undergraduate degree in Chemistry and her Ph.D. in Biomolecular Chemistry at UW-Madison. Her postdoctoral work was at the Department of Biochemistry and NMR Facility at Madison. Her current research is focused on metabolomics and developed metabolic dynamic platform (MDP) that combines NMR spectroscopy with stable isotope assisted labeling for tracing pathways in vivo. Dr. Assadi-Porter’s research has resulted in several patents and many peer-reviewed publications.

Copie V. Montana State University Bozeman MT USA
Regional Editors Asia cmb_ebm_tang-hairu_001 Tang H. Fudan University Shanghai China

Professor Tang is a Distinguished Professor in Molecular Phenomics at Fudan University. After earned his PhD from University of London (1994), he worked at Institute of Food Research, Imperial College London and Chinese Academy of Sciences for 20 years with 190 peer-reviewed scientific publications on metabonomics. He was awarded "National Distinguished Young Scholars Award (2008)", "National Talent Award (New Century Program for National Talents, China) (2009)", "Wang Tianjuan Award in NMR Spectroscopy (2010)". He is a Fellow the Royal Society of Chemistry, Editorial Board Member for J Proteome Res, Metabolomics, Arch Pharm Res, and Associated Editor for NPJ-Molecular Phenomics.

cmb_ebm_wang_001 Wang Y. Chinese Academy of Sciences Wuhan China

Prof Wang graduated in China and got her PhD in 1997 from University of East Anglia, UK. After two years of postdoctoral experience at Institute of Food Research, UK, she worked at Imperial College London for 7 years working in the field of metabonomics. 2007, she joined Wuhan Institute Physics and Mathematics, Chinese Academy of Sciences, as professor. Her research interests are metabonomics method development and application the technique in infectious disease, metabolic disease and clinical settings. She has published more than 120 peer reviewed papers.

Australia cmb_ebm_schirra_001 Schirra H. University of Queensland Queensland Australia

Dr. Schirra is a Research Fellow at the University of Queensland’s Centre for Advanced Imaging (CAI) and administers CAI’s facility for NMR-based metabolomics. He studied Chemistry in Frankfurt, Germany, and received his PhD in Biochemistry from the ETH Zurich, Switzerland. In 1999, he joined UQ, where he was awarded an Australian Research Council Postdoctoral Fellowship and a Queensland Smart State Fellowship. Dr Schirra’s research in Metabolic Systems Biology focuses on the basic principles of metabolic regulation and the role they play in fundamental biological processes, environmental change, and disease development. Dr Schirra is Board Member of the Australian and New Zealand Society for Magnetic Resonance, committee member of the Australian and New Zealand Metabolomics Network, and Co-chair of the 13th International Conference of the Metabolomics Society in Brisbane 2017.

Germany cmb_ebm_Bergen_001 von Bergen M. The Helmholtz Centre for Environmental Research Leipzig Germany

Dr. Martin von Bergen is Head of the Department of Molecular Systems Biology at the Helmholtz Centre for Environmental Research and holds a joint professorship for Functional Proteomics at the University of Leipzig. He has more than 20 years of experience in the structural and functional analysis of single proteins and on the global level. He has also 10 years supervised research in metabolomics. Dr. von Bergen earned his PhD in the Max-Planck Society,where he focussed on the analysis of Tau Protein and received his Habilitation on this topic from the University of Hamburg. He has authored more than 240 manuscripts (status at 10.10.2016), leading to h-index of 35.

North America cmb_ebm_raftery_001 Raftery D. University of Washington Seattle, WA USA

Dr. Raftery is a Medical Education and Research Endowed Professor at the University of Washington, School of Medicine, and Member of the Fred Hutchinson Cancer Research Center in Seattle WA. Previously, he was Professor of Chemistry at Purdue University. He currently directs the Northwest Metabolomics Research Center at UW, and is the founder and CSO of Matrix-Bio, Inc. Dr. Raftery’s research is focused on the development of new MS and NMR methods and their application to a range of studies in metabolomics profiling including the identification of early disease biomarkers, and exploration of systems biology in cells and mitochondria.

Editorial Board Members cmb_ebm_ametaj_001 Ametaj B. University of Alberta Alberta AB Canada

Dr. Ametaj is a Professor of Animal Physiology at University of Alberta, Canada. He received his PhD at Iowa State University, Ames, Iowa, USA and did postdoctoral training at Iow State University, Purdue University, Indiana, and Cornell University, New York. His research expertise is in nutritional immunology. His research activity includes identification of biomarkers of disease risk in dairy cows and development of new technologies for prevention of transition cow diseases.

cmb_ebm_bearden_001 Bearden D. National Institute of Standards and Technology (NIST) Charleston SC USA

Dr. Daniel W. Bearden is a senior Research Chemist for the National Institute of Standards and Technology, Materials Measurement Laboratory, Chemical Sciences Division at the Hollings Marine Laboratory in Charleston, SC. Previously Dr. Bearden served as a research Chemist for the National Oceanographic and Atmospheric Administration (NOAA) in Charleston. He is also an adjunct research professor at the Medical University of South Carolina in the Marine Biomedicine and Environmental Sciences center. His current research interests include NMR-based environmental metabolomics, nutrition metabolomics, quantitative NMR spectroscopy and metabolomics data quality issues.

Bruschweiler R. Ohio State University Columbus OH USA cmb_ebm_caldarelli_001 Caldarelli S. Aix Marseille University Marseille France

53 years old, Chemistry professor of Chemistry - University of Aix Marseille. Research interests: NMR methodology (mixture analysis) and applications (metabolomics, supramolecular species), advanced signal processing and physical chemistry of chromatography. About 90 publications in international journals - 4 book chapters. Graduated (1992 C.A. Veracini) from the University of Pisa, post-docs at UC Berkeley (A. Pines), Lausanne (profs. Merbach and Bodenhausen), ENS Lyon (L. Emsley). CNRS Institut de Recherche sur la Catalyse (1997-2001). Professor Aix-Marseille Université since 2001.International Advisory Board: Analytical and Bioanalytical Chemistry (2017-2019).

Chen H. East China University of Technology Nanchang China cmb_ebm_costantini-s_001 Costantini S. National Cancer Institute Naples Italy

Dr. Susan Costantini has a degree in Chemistry, a PhD in Computational Biology and a Specialization in Clinical Pathology and Biochemistry. She is professor of Biochemistry and Bioinformatics. Since 2008, she is a Researcher at National Cancer Institute of Naples "Pascale Foundation". Dr. Costantini is currently studying the cytokinomic and metabolomic profile by 1H-NMR in various cellular systems, biological fluids and tissues of cancer patients. Moreover, her research activities include the application of systems biology approaches to integrate “omics” data by computational methods.

cmb_ebm_devarakonda_001 Devarakonda V.S. ScieGen Pharmaceuticals lnc Hauppauge NY USA

Dr. Venkata S. Devarakonda is amongst the top scholars in the field of analytical chemistry and is privileged to be selected amongst the few experts that served on Current Metabolomics editorial board. He was chosen for this role on the basis of his valuable contributions to chemical and pharmacological research, his lengthy record of peer review service, and his general expertise on a variety of advanced scientific topics. Current Metabolomics owes Dr. Devarakonda a great debt for his invaluable contributions as an editorial board member. Dr. Devarakonda outstanding performance and leadership skills are much appreciated in the scientific community.

cmb_ebm_giradeau_001 Giraudeau P. Université de Nantes Nantes France

Dr. Giraudeau is Associate Professor of Chemistry at the University of Nantes, France. He has more than 10 years of experience with the development of quantitative NMR methods applied to analytical chemistry, and particularly to metabolomics and fluxomics. Previously, Dr. Giraudeau has been a post-doctoral research associate at the Weizmann Institute of Science (Israel). Dr. Giraudeau has authored more than 60 manuscripts and 1 patent. He is the vice-president of the Francophone metabolomics and fluxomics association (RFMF) and a member of the AMPERE committee. Dr. Giraudeau teaches NMR spectroscopy at the University of Nantes.

cmb_ebm_gowda_001 Gowda G.A.N. University of Washington Seattle WA USA

My research interests are in the area of metabolomics, both methods development and applications focusing investigations of human health and diseases. Our methods development, utilizing nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS) techniques, is focused on the analysis of metabolites in complex biological mixtures from humans, animal models and cell lines. We also combine NMR and MS techniques to exploit their strength to unravel the biological complexity and quantify unknown metabolites. We are also interested in enhancing the NMR’s detection sensitivity and resolution with a view to expand the pool of quantifiable metabolites for metabolomics applications.

cmb_ebm_gronwald_001 Gronwald W. University of Regensburg Regensburg Germany

I was born and grew up in Hamburg in northern Germany. After completion of high school I studied chemistry at the Technical University of Braunschweig, Germany. At that time I became fascinated by the possibilities that computational approaches together with experimental methods offer for the study of biological objects such as 3D protein structures and small organic molecules. Something I pursued from that time on through my whole career first as a Ph.D. student, as a post-doc at the University of Alberta in Canada and now with my own research group at the University of Regensburg in Germany.

Grootveld M. De Montfort University Leicester UK cmb_ebm_h-gu_001 Gu H. University of Washington Seattle WA USA

Dr. Haiwei Gu is a Research Assistant Professor at the University of Washington. His research interests focus on NMR- and MS-based metabolomics and its applications in early disease diagnosis, drug metabolism, and biological sciences. His projects include the development, optimization, and applications of MS and NMR methods for both qualitative and quantitative measurements. Meanwhile, he has extensive experience with advanced statistical analysis and modeling methods. Currently, he is working closely with a number of clinical researchers and practitioners in various studies for identifying metabolic markers, which are useful for detecting cancer recurrence, investigating cancer metabolism using cell/mitochondria models, examining metabolic remodeling during pressure-overload hypertrophy, comprehensively profiling age-dependent changes of cardiac metabolites, etc.

cmb_ebm_hage_001 Hage D.S. University of Nebraska Lincoln NE USA

Dr. Hage is the James Hewett University Professor of Chemistry at the University of Nebraska-Lincoln. Dr. Hage’s general research interests involve the design and use of affinity-based separations in high-performance liquid chromatography, capillary electrophoresis and other systems for clinical, pharmaceutical, and environmental analysis. Dr. Hage received his PhD in Analytical Chemistry from Iowa State University and BS degrees in Chemistry and Biology from the University of Wisconsin-La Crosse. He received the 2015 Award from the Eastern Analytical Symposium for Outstanding Achievements in Separation Science and has over 250 publications in this field.

cmb_ebm_s-hu_001 Hu S.S. UCLA School of Dentistry Los Angeles CA USA

Dr. Shen Hu's research interests are in the area of cancer proteomics/metabolomics focusing on understanding the molecular mechanisms of cancer invasion/metastasis and developing diagnostic/therapeutic applications using mass spectrometry and protein microarray technology. His lab is also developing biomarkers for autoimmune diseases and studying single cell proteomics and cancer stem cells.

Keshari K.R. Memorial Sloan Kettering Cancer Center New York, NY USA cmb_ebm_dkumar_001 Kumar D. Sanjay Gandhi Post-Graduate Institute of Medical Sciences Lucknow India

Dinesh Kumar, PhD, M.Sc.Dr. Dinesh started his research career in Aug 2005 in the field of biomolecular NMR and currently, he is working as an Assistant Professor at the Centre of Biomedical Research (CBMR), Lucknow, India. The primary area of his research is NMR based metabolomics for disease metabotyping i.e. to identify the disease specific metabolic signatures and to appraise their utility in clinical diagnosis and surveillances. Parallelly, he is also involved in developing NMR methods and protocols for rapid structural and functional studies of proteins. During his 11 years of research career, he has authored more than 35 research publications, several conference papers, 1 patent and has delivered several invited lectures. His research work in the area of biomolecular NMR, particularly, the developed NMR methodologies have been well recognized both nationally as well as internationally as demonstrated by his getting "2011 Eli Lilly Outstanding Thesis Award in Structural Biology" and CBMR-NMRS gold medal from National Magnetic Resonance Society (NMRS), India for the year 2013.

cmb_ebm_vkumar_001 Kumar V. All India Institute of Medical Sciences New Delhi India

Dr. Virendra Kumar is an Associate Professor in the Department NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi. He received Gold Medal for his Ph.D. thesis on MR studies of prostate cancer from AIIMS, New Delhi and was a Cancer Imaging postdoctoral fellow, Department of Cancer Imaging and Metabolism, Moffitt Cancer Center, Tampa, FL, USA. Dr. Kumar is applying Radiomics, NMR metabolomics and in vivo MR methods to understand the different metabolic changes in cancer and their potential diagnostic role.

cmb_ebm_haitao-lu_001 Lu H. Shanghai Jiao Tong University Shanghai China

Dr. Haitao Lu is a professor of metabolomics and microbial metabolism in Shanghai Jiao Tong University in China, where he also performs the role of Faculty Director, Laboratory for Functional Metabolomics Science. Over the past 8 years, Dr. Lu has authored and co-authored 40+ peer-reviewed papers in various high-profile journals, such as Mass Spectrometry Reviews, Journal of Proteome Research, etc. Dr. Lu has secured three national competitive research grants and 5 research fellowships from different funding agencies. Dr. Lu is member of Editorial Board of Bioanalysis, Phytomedicine, Frontiers in Microbiology, Current Metabolomics, and also acts as an expert for NSFC, NHMRC.

Marini F. University of Rome "La Sapienza" Rome Italy cmb_ebm_markley_001 Markley J.L. University of Wisconsin-Madison Madison WI USA

Dr. Markley is Steenbock Professor of Biomolecular Chemistry in the Biochemistry Department, University of Wisconsin-Madison. He holds a PhD in Biophysics from Harvard University and was an NIH Postdoctoral Fellow at the University of California, Berkeley. He spent 12 years on the faculty of the Chemistry Department at Purdue University before moving to Madison. Dr. Markley has authored more than 550 publications. He is the founder and head of both the Biological Magnetic data Bank (BMRB) and the National Magnetic Resonance Facility at Madison, each supported by the National Institute General Medical Science, National Institutes of Health.

cmb_ebm_meikle_001 Meikle P. Baker IDI Heart and Diabetes Institute Melbourne Australia

A/Prof Peter Meikle is a NHMRC Senior Research Fellow. He is leader of the Metabolism Program and Head of the Metabolomics Laboratory at Baker IDI Heart and Diabetes Institute. He holds affiliate positions at the University of Melbourne and Monash University. The Metabolomics Laboratory has a focus on the dyslipidemia and altered lipid metabolism associated with obesity, diabetes and cardiovascular disease and its relationship to the pathogenesis of these disease states. This work is leading to new approaches to early diagnosis and risk assessment as well as the development of new lipid modulating therapies for chronic disease.

Miccheli A. Sapienza University of Rome Rome Italy cmb_ebm_pappalardo_001 Pappalardo L. American University of Sharjah Sharjah United Arab Emirates

Lucia Pappalardo has an extensive research background on the analysis of three-dimensional structures of biologically active molecules by nuclear magnetic resonance (NMR). She has worked as Research Associate and Fellow at the Scripps Research Institute, Max Planck Institute, CNR, Stockholm University and Syddansk University. At AUS, she has worked on the removal and recovery of heavy metals from wastewaters by using local sand. She has a collaboration program with Princeton University on metabolomics studies by NMR. Her teaching interests are physical chemistry, general chemistry and biophysics/biochemistry.

Pelczer I. Princeton University Princeton NJ USA cmb_ebm_pesi_001 Pesi R. University of Pisa Pisa Italy

I was born in Lucca in 1959.My city is famous for its intact Renaissance-era city walls that can be walked or cycled in the shade of secular trees.I’ m married to Luciano, an insurance agent, and we have a son, Lorenzo, who attends the faculty of Psycolgy in Turin.I love animals and the outdoor life.I have been a member of equal opportunities committees, so, for many years I have been involved in gender studie.

cmb_ebm_ramamoorthy_001 Ramamoorthy A. University of Michigan Ann Arbor MI USA

Dr. Ayyalusamy Ramamoorthy obtained his Ph.D. in Chemistry in 1990 from the Indian Institute of Technology (Kanpur, India) working on the development of NQR spectroscopy. He subsequently moved to the Central Leather Research Institute (a national research laboratory in Madras/Chennai, India) as a Fellow to develop scalar coupling based NMR methods. In 1992, he joined JEOL Ltd. (Tokyo, Japan) as a Scientist to develop NMR techniques for studies on biological solids. He then joined Professor Stanley Opella’s group (University of Pennsylvania, Philadelphia) in 1993 to further develop and apply solid-state NMR techniques for atomic-level resolution imaging of membrane proteins. In 1996, he joined the University of Michigan in Ann Arbor where he currently is the Robert W. Parry Collegiate Professor of Chemistry and Biophysics. His main research interests are on the development and applications of NMR spectroscopy to study dynamic structures and function of membrane proteins and amyloid proteins, and cancer metabolomics by NMR. More details about his current research can be found at

cmb_ebm_rattray-njw_001 Rattray N.J.W. Strathclyde Institute of Pharmacy and Biomedical Sciences Scotland UK

Dr. Nicholas Rattray is currently a Chancellor’s Fellow and Lecturer (Assistant Professor) of Clinical Metabolomics at the University of Strathclyde, Scotland. He received his MChem in Medicinal Chemistry from the Manchester Metropolitan University, was awarded a Ph.D. in Biophysics from the University of Manchester and subsequently went on to technician and postdoctoral positions within the Manchester Institute of Biotechnology. Before taking up his current position at UoS he was a faculty level Associate Research Scientist within the School of Public Health at Yale University and has a research focus on how metabolism breaks down as we age. He has over 50 peer-reviewed articles and served on the Board of Directors of the Metabolomics Society in 2015.

cmb_ebm_ren_001 Ren J. Advanced Imaging Research Center Dallas TX USA

Dr. Ren is an Assistant Professor in the Advanced Imaging Research Center at UT Southwestern Medical Center. Currently Dr. Ren is leading the development of MRS/MRI methods at ultra-high field 7T for imaging metabolites and metabolic activities in human organs. Dr Ren’s study focus on answering fundamental questions such as how different metabolic pathways interact and how various metabolites exchange among different compartments to meet energy demand or cause energy deficit as seen in a variety of metabolic diseases. Dr Ren has extensive research experience studying brain, liver and skeletal muscle, using 1H, 13C and 31P MRS.

cmb_ebm_rovnyak_001 Rovnyak D. Bucknell University Lewisburg PA USA

"A native of Charlottesville, VA, David Rovnyak is a Professor of Chemistry at Bucknell University. He obtained his Ph.D. at the Massachusetts Institute of Technology focusing in solid state NMR, and pursued post-doctoral work at the Harvard Medical School on protein NMR technology. Research in his laboratory includes developing data sampling technology for NMR, studying the structures and thermodynamics of guest-host complexes, and developing methods and applications of NMR metabolomics. He is also Assistant Editor of Concepts in Magnetic Resonance and is interested in science outreach and promoting undergraduate research, and he can be found as 'NMR_guy' on twitter."

cmb_ebm_ryan_001 Ryan E.P. Colorado State University Fort Collins CO USA

Elizabeth P. Ryan is an Associate Professor of Toxicology and Nutrition in the Department of Environmental and Radiological Health Sciences located in the College of Veterinary Medicine and Biomedical Sciences at Colorado State University/Colorado School of Public Health She conducts translational research using metabolomics and spanning laboratory, animal models, and clinical trials for companion animals and human health across the lifespan.

cmb_ebm_saha_001 Saha I. National Institute of Technical Teachers' Training & Research Kolkata India

Dr. Saha is a faculty member in the department of Computer Science and Engineering, National Institute of Technical Teachers' Training & Research (NITTTR), Kolkata, India. He has done his postdoctoral research at the National Research Council, Italy and University of Wroclaw, Poland. He was the visiting research scientist at CWI, Netherlands, INRIA France, IIT-CNR, Italy, ICM in University of Warsaw (UW), Poland. He received his Ph.D. degrees in Computer Science and Engineering and Bioinformatics from Jadavpur University, India and Polish Academy of Sciences, Poland after doing B.Tech and M.Tech. He has co-authored about 50 research papers in various International Journals and Conferences. Dr. Saha is an active member of the board of reviewers for several International Journals. His research interest includes Computational Biology, Computational Intelligence, Machine Learning, Education Technology, Image Processing and Pattern Recognition.

Serkova N.J. University of Colorado Hospital Aurora CO USA cmb_ebm_shah_001 Shah M. Albany College of Pharmacy and Health Sciences Albany NY USA

Dr. Shah is an assistant professor at the Albany College of Pharmacy and Health Sciences, Albany, NY. He has over 10 years of experience in structural biology and drug metabolism. Dr. Shah's research is focussed on drug metabolizing cytochrome P450 enzymes and has authored 21 publications. Dr. Shah holds a Ph.D. in structural biology and drug discovery from the University of Nottingham, UK.

cmb_ebm_sherry_001 Sherry D. University of Texas Southwestern Medical Center Dallas TX USA

A. Dean Sherry, PhD, is Director of the Advanced Imaging Research Center at the University of Texas Southwestern Medical Center, Professor of Chemistry at the UT Dallas, and Professor of Radiology at UT Southwestern. He also holds the Cecil & Ida Green Distinguished Chair in Systems Biology at UT Dallas. Dr. Sherry has been recognized for his research in two major areas: the development of 13C NMR tracers of metabolism in cells, animals and humans and in developing novel MRI agents that respond to physiology or metabolism including Gd3+-based agents, PARACEST agents and hyperpolarized agents.

Sumner S.C.J. Research Triangle Park NC USA cmb_ebm_tschaplinski_001 Tschaplinski T. Oak Ridge National Laboratory Oak Ridge TN USA

Dr. Tschaplinski is a plant molecular physiologist experienced in biochemistry, specifically the application of mass spectrometry to research problems in genomics, bioenergy crop production, environmental stress physiology, and plant-microbe signaling. Current research includes metabolomics for phenotypic characterization of genetically-modified Populus, Arabidopsis, Eucalyptus, Castanea, switchgrass, and numerous bioenergy-relevant microbial species. Research targets include the application of genomic tools for the accelerated domestication of Populus to increase drought tolerance and biomass productivity on marginal sites, and to manipulate bioproduct formation. Most recent activities include characterizing the molecular basis of plant-microbe (bacterial and fungal) symbiotic relationships in contrast with pathogenic relationships.

cmb_ebm_valentini_001 Valentini M. Sultan Qaboos University Muscat Oman

I graduated in Physical Chemistry at the University of Perugia (Italy) in 1998 and I received the PhD in Inorganic Chemistry from the Swiss Federal Institute of Technology (ETH - Zurich) in 2001 under the supervision of Prof. P.S. Pregosin. After a decade as researcher at the Magnetic Resonance Laboratory of the ARC in Italy I joined recently the Department of Chemistry of the Sultan Qaboos University (Sultanate of Oman). I am authors of about 60 peer reviewed papers with an h index of 22 and about 2000 citations.

cmb_ebm_vogel_001 Vogel H.J. University of Calgary Calgary AB Canada

Hans Vogel is an NMR spectroscopist who received his original academic training in the Netherlands, Canada and Sweden. He is currently a Full Professor at the University of Calgary. Over his career he has made numerous contributions to our understanding of regulatory calcium binding proteins, bacterial iron metabolism and the mode of action of antimicrobial peptides. Early on he was involved in 'in vivo NMR spectroscopy' and this experience has helped him to enter the metabolomics field when it emerged. His current interests are in clinical metabolomics applications of NMR, GC-MS and ICP-MS of patient samples in the areas of cancer and infectious diseases.

cmb_ebm_wishart_001 Wishart D. University of Alberta Edmonton AB Canada

Dr. David Wishart is a Professor in the Departments of Biological Sciences and Computing Science at the University of Alberta. He is also an adjunct professor in the Department of Laboratory Medicine and Pathology as well as the Faculty of Pharmacy and Pharmaceutical Sciences. Dr. Wishart is the Director of Canada’s national metabolomics laboratory – The Metabolomics Innovation Centre (TMIC). His research interests span many areas including metabolomics, structural biology, bioinformatics, proteomics and prion biology. Dr. Wishart has authored over 300 publications, with over 39,000 citations and an h-index of 78.

cmb_ebm_l-yu_001 Yu L. University of Iowa Iowa City IA USA

Dr. Yu is Adjunct Professor of Biochemistry and Director of Carver College of Medicine NMR facility. He has 28 years of experiences in structural biology and NMR spectroscopy to study biomolecular structure and function. Previously, Dr. Yu worked at Abbott Laboratories for 17 years on drug targets involved in anti-infectious diseases, cancers, metabolic and neuronal diseases. Notably, Dr. Yu has coauthored 70 papers including 4 in Science, 1 in Nature, 2 in eLife, 2 in Nature Structural Biology, 1 in Nature Chemical Biology, and 3 in PNAS. His current research interests include muscular dystrophy, metabolomics, drug discovery, and protein-ligand recognition.

Yu T. Emory University Atlanta GA USA cmb_ebm_l-zhao_001 Zhao Y.-Y. Northwest University Shaanxi China

Dr. Ying-Yong Zhao (PhD, MD) is professor at Department of Traditional Chinese Medicine, Northwest University in China. Zhao has authored more than 100 peer-reviewed publications and three books. He received several awards including Sanofi Young biological drugs Award and Fifteenth SERVIER Youth Pharmacology Award. He serves as an editor-in-chief of Journal of Nephrology Advances and editorial board member for 13 international journals including Journal of Nephrology & Therapeutics, Current Metabolomics and Journal of Nephrology and Urology Research. He is a reviewer of more than 30 famous international journals, including Nature Review Nephrology, Kidney International and CJASN in the area of pharmacology and metabolomics studies. His areas of expertise include pharmacology and metabolomics from natural products. His work is mainly focus on chronic kidney disease and therapeutic effect of natural products by pharmacology and metabolomics. He also is studying the oxidative stress, inflammation, and pro-fibrotic pathways of chronic kidney disease.

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