Full Text Inquiry
ePub [ahead of print] Inquiry Form:

Thank you for your interest in the full text of this ePub article. The full text of this article is not available as yet. Could you please complete and submit the brief EPub full text inquiry form given below and one of our representatives will contact you shortly with details of the article, it's availability, and price on order.

Article Detail:

Potential role of bioactive lipids in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, which involves a pathological inflammatory response against articular cartilage in multiple joints throughout the body. It is a complex disorder associated with comorbidities such as depression, lymphoma, osteoporosis and cardiovascular disease (CVD), which significantly deteriorate patients’ quality of life and prognosis. This has ignited a large initiative to elucidate the physiopathology of RA, aiming to identify new therapeutic targets and approaches in its multidisciplinary management. Recently, various lipid bioactive products have been proposed to have an essential role in this process; including eicosanoids, specialized pro-resolving mediators, phospholipids/sphingolipids, and endocannabinoids. Dietary interventions using omega-3 polyunsaturated fatty acids or treatment with synthetic endocannabinoids agonists have been shown to significantly ameliorate RA symptoms. Indeed, the modulation of lipid metabolism may be crucial in the pathophysiology and treatment of autoimmune diseases.

Journal Title: Current Pharmaceutical Design

Price: $95

Inquiry Form

1 + 18 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.