Thyroid Cancer: A Clinical Overview and A Useful Laboratory Manual

Thyroid Cancer of Parafollicular Origin: Medullary Carcinoma

Author(s): Maria G. Castagna

Pp: 76-84 (9)

DOI: 10.2174/9781608057498113010010

* (Excluding Mailing and Handling)

Abstract

Medullary thyroid carcinoma is a tumor of the parafollicular C cells which accounts approximately 3% of thyroid cancer. It may occur as sporadic form or hereditary cancer both alone or associated with syndromes. In this chapter, epidemiology, genetic, diagnosis and treatment of medullary thyroid cancer will be discussed.


Keywords: Medullary thyroid cancer, MEN2A, MEN2B, RET point mutations.

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