Abstract
Polycystic kidney disease (PKD) is characterized by uncontrolled cellular proliferation, leading to fluid accumulation, extracellular matrix remodeling, and cyst formation with progressive kidney damage that leads to renal failure and death. Besides the kidney, other organs, such as the liver, the heart, and vasculature, are damaged.
Keywords: ADPKD, Autosomal dominant, Autosomal recessive, Heritage, Monogenic disease.
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