Inflammation in Kidney Diseases

Pp: 36-48 (13)

* (Excluding Mailing and Handling)

Abstract

Inflammation is a complex network of interactions between renal parenchymal cells and resident immune cells, such as macrophages and dendritic cells, in conjunction with the recruitment of circulating monocytes, lymphocytes, and neutrophils. Inflammation is an important defense mechanism intended primarily to detect and fight pathogens; resident and circulating immune cells can interact with renal parenchymal cells to trigger the inflammatory response when subjected to stress, leading to irreversible tissue damage and organ failure. Although more evidence of the impact of exercise and omega-3 supplementation on the inflammatory status of these patients has yet to be generated, current evidence suggests that these types of interventions could have a beneficial impact on reducing inflammatory reactions in this population.

Keywords: Adaptative immune system, Dendritic cells, Immune cells, Innate immune system, Interleukins.

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