Andrographolide and its Analogs: Botanical Sources, Phytochemistry, Pharmacology, and Biotechnology

Andrographolides – An Overview

Author(s): S. Karuppusamy*, T. Pullaiah and Vinod K. Nelson

Pp: 1-9 (9)

DOI: 10.2174/9789815256567124010003

* (Excluding Mailing and Handling)

Abstract

The genus Andrographis is usually bitter and is the source of several diterpenoids, of which water-soluble labdane diterpenoid is andrographolide. Among the various diterpene lactones reported from most of the species of Andrographis, andrographolide is considered one of the major bioactive secondary metabolites. The genus Andrographis possesses diverse phytochemical constituents with significantly interesting biological potentials. Diterpenes, flavonoids, xanthoflavones, iridoids, and other groups of miscellaneous compounds have been characterized from the various species of Andrographis. Andrographolide has been isolated as a notable major phytochemical compound among the andrographolides, which is a common diterpene flavonoid with phytochemical constituents and therapeutic activities.


Keywords: Andrographolide, Andrographis, Anticancer, Ethnobotany, Pharmacology, Propagation.

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