Abstract
The COVID-19 pandemic has led to widespread illness, death, and economic disruption worldwide, leading to a critical need for effective treatments, vaccines, and diagnostic tools. SARS-CoV-2, belonging to the class of β-CoVs, is the virus accountable for COVID-19, and mediates entry into the host cell via its surface spike protein. Understanding its replication and pathogenesis is crucial for developing effective treatments and curbing the microbe’s spread. Here, we dive deep into the genomic organisation of the SARS-Cov2 virion and its various structural components, highlighting the molecular mechanism involved in replication, ultimately leading to pathogenesis.
Keywords: COVID-19, Diagnostic, Genomics, Pandemic, Pathogenesis, SARSCoV-2, Vaccines.