Abstract
Obesity and diabetes impair skeletal muscle metabolism, muscle atrophy, and contractile function, but the intracellular mechanisms have not been clarified fully. Increasing evidence suggests that oxidative stress is associated with obesity and diabetes. Depending on the pathological condition, stress may be affected to a greater extent. Muscle oxidative stress has been implicated in lipid species composition in type 2 diabetes. This chapter discusses the impact of metabolic disease on the regulation of lipid species and oxidative stress.
Keywords: Ferroptosis, Lipid species, Oxidative stress, Phospholipid, Skeletal muscle.
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