Indicator Displacement Assays (IDAs): An Innovative Molecular Sensing Approach

IDA-based Differential Sensory Arrays and Assays

Author(s): Ishfaq Ahmad Rather* and Rashid Ali * .

Pp: 143-165 (23)

DOI: 10.2174/9789815165913124010008

* (Excluding Mailing and Handling)

Abstract

For the pattern-based recognition of various metal species and bioanalytes, nature has stimulated an emergent supramolecular domain of synthetic receptor arrays and assays. It is not always necessary for a synthetic receptor to be selective for a particular analyte in a differential receptor array, but the inclusive signal response from a typical sensory array must be diagnostic for the target analyte. This new category of molecular recognition is rapidly advancing with various groups constructing novel array platforms as well as receptors. Owing to easy operation and better selectivity, the sensory array has gained significant attention in the realm of complex system analysis. Besides the conceptual background, the authors have elaborated on the applications of various differential arrays through numerous examples. The authors believe that this chapter devoted to IDA-based differential sensory arrays and assays will bring a new episode of IDA-based chemosensors for target analytes. 


Keywords: Analyte, Anion sensing, Complex mixtures, Colorimetric indicator, Differential sensory array, Diagnostic patterns, Detection, Differential sensing, Differential anion sensing, Fingerprint response, High-throughput screening, Immobilized sensory, Molecularly imprinted polymers, Molecular recognition, Optical signatures, Supramolecular receptors, Sensitive, Selective, Supervised pattern recognition protocols, Small molecules.

Related Journals
Related Books
© 2024 Bentham Science Publishers | Privacy Policy