The Role of Seaweeds in Blue Bioeconomy

Anti-Cancer Properties of Pure Compounds Isolated From Seaweeds

Author(s): Don Ciril Harischandra Hiruni Sadunika Kumarasinghe, Thilina L. Gunathilaka, Prasad Jayasooriya and Kalpa W. Samarakoon * .

Pp: 155-170 (16)

DOI: 10.2174/9789815223644124010011

* (Excluding Mailing and Handling)

Abstract

Cancer is a major public health concern, and there are no entirely effective treatments. Therefore, natural product-based alternative therapies have been suggested as effective therapeutics against cancer. Marine algae are a promising research tool considered a natural source of bioactive compounds embedded in marine ecology. Algae synthesize a vast variety of bioactive compounds, including polysaccharides, polyphenols, sterols, alkaloids, flavonoids, tannins, proteins, essential fatty acids, enzymes, vitamins, and carotenoids. These pure compounds are composed of intricate structures and exhibit a wide array of possible capabilities, including anticancer potency, in a plethora of in vitro and in vivo settings. Further, these bioactive constituents derived from seaweeds target crucial molecules that control the development of cancer. So, this chapter mainly focuses on the anti-cancer properties of pure compounds isolated from seaweeds and their therapeutic potential against a wide array of cancer types.


Keywords: Anti-angiogenesis, Anti-cancer, Apoptosis, Cancer therapeutics, Cell culture, Cell-cycle arrest, Chlorophyta, Seaweeds, Natural products, Phaeophyta, Phlorotannins, Polysaccharides, Primary metabolites, Rhodophyta, Secondary metabolites, Therapeutics.

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