Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 2)

Scaffolds in Vascular Tissue Engineering Research

Author(s): Jun W. Heng, Ubashini Vijakumaran, Rohaina C. Man and Nadiah Sulaiman * .

Pp: 119-139 (21)

DOI: 10.2174/9789815179330124010010

* (Excluding Mailing and Handling)

Abstract

Scaffolds represent one of the key components in the tissue engineering triad. Construction of a vascular graft begins with the scaffold that acts as the base building material. Whether natural or synthetic, selecting the right scaffold material is essential to ensure the structural integrity of a graft. The structural integrity could further be strengthened with the addition of cells and regulatory signals that make up the whole tissue engineering triad. In this chapter, a selection of scaffold materials is discussed, and cell seeding strategies are later elaborated, covering the principle of the tissue engineering triad in vascular research.


Keywords: Blood vessel, Scaffold, Small diameter vascular graft, Tissue engineering triad, Vascular scaffold.

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