Research Methodology and Project Management in Biotechnology

Newer Technologies in Molecular Biology

Author(s): Simmi Kharb*, Akshat Singh*, Abhyuday Singh* and Deepa Kharb * .

Pp: 300-366 (67)

DOI: 10.2174/9789815080742123010011

* (Excluding Mailing and Handling)

Abstract

Technical advances began with the advent of array comparative genomic hybridization and single nucleotide polymorphism arrays and are enabling researchers to identify disease-associated genetic variants by virtually scanning the entire genome. With the help of these technologies, it is now possible to screen for common genetic variants and even rare small deletions and duplications i.e., microdeletions and microduplications. This has led to a virtual explosion of gene identifications. This chapter aims to provide an overview of new technologies.


Keywords: Antisense RNA, Antisense therapy, Gene silencing, Jumping gene, Bioterrorism, Bioweapons, cytogenetic, DNA methylation, Pharmacogenetics, Pharmacogenomics, Nutrigenomics.

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