Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1)

Modification and Treatment of Wound Dressing Material

Author(s): Abdul Hair Ainul Hafiza, Mohamad-Khalid Khairunnisa-Atiqah, Nyak Syazwani Nyak Mazlan, Kushairi Mohd Salleh* and Sarani Zakaria * .

Pp: 112-130 (19)

DOI: 10.2174/9789815123104123010011

* (Excluding Mailing and Handling)

Abstract

The utilisation of bio-based materials in constructing an advanced wound dressing for regenerative medicine is not new. Due to the fundamental principle of tissue engineering in regenerative medicine, bio-based wound dressing formulated from by-products or animal or plant wastes could contribute significantly to healing processes. Bio-based materials help to regenerate and replace damaged tissues and shorten the recovery period without frequent dressing changes. The bio-based dressing development begins with a small-scale benchwork that focuses on modifying and treating the bio-based material before it is clinically applied for wound treatment procedures. The modified bio-based materials then turn into functional wound dressing in various forms such as hydrogel, membrane, sponges, film, or fibres. The dressing’s therapeutic healing properties can be enhanced by subjecting it to physical, chemical, and biological treatments. The dressing principle must abide by tissue engineering needs and offer a broader range of alternatives that can clinically treat different types of wounds based on different etiology. Therefore, this book chapter highlights the advantages of a bio-based material and its modification for wound dressing for tissue engineering purposes in regenerative medicine.


Keywords: Bio-based material, Chemical treatment, Green product, Physical treatment, Tissue engineering, Wound healing.

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