Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside (Part 1)

Wound Healing Utilizing Electrical Stimulation Technique: Towards Application of Dielectrophoresis

Author(s): Nur Nasyifa Mohd Maidin, Revathy Deivasigamani, Muhamad Ramdzan Buyong, Nur Athirah Mohd Som and Mohd Ambri Mohamed * .

Pp: 96-111 (16)

DOI: 10.2174/9789815123104123010009

* (Excluding Mailing and Handling)

Abstract

Diabetes is a metabolic disorder characterised by long-term hyperglycemia caused by insulin resistance [1]. According to scientific studies, the number of people with diabetes climbed from 30 million in 1985 to 177 million in 2000 and is expected to increase to 552 million by 2030 [2, 3]. Diabetic patients suffer from impaired or delayed wound healing due to a few factors leading to the development of chronic wounds. Chronic wound management is becoming an economic burden on the healthcare system. With the rising prevalence of chronic diabetic wounds, finding effective treatment strategies and advancing therapy are critically important. Although the exploration of electrostimulation therapy for wounds is only very recent, it is a promising approach to expedite wound healing. With recent advancements in wearable device technology, a new treatment strategy that integrates electrical stimulation and biomaterial dressing has been adopted.


Keywords: Dielectrophoresis, Electrical stimulation, Electric field, Stimulation therapy, Wound healing.

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