Abstract
The in-silico study on protein-peptide docking involves initiating the biomolecular interaction to identify compatible peptides with antibacterial properties. The current research elucidates a computational module for the discovery. The proteinpeptide docking of marine peptides against the marine bacteria and the gills of teleost fish in CABS-DOCK resulted in a compatible docked structure with the highest accuracy. Protein-peptide docking resulted in maximum compatibility for “ELLVDLL” derived from marine bacteria than “FIHHIIGGLFSVGKHIHGLIHGH” derived from the tapaila gills of teleost fish concerning receptors of resistant bacterial strains.
Keywords: Global docking, PDB, Peptides, Protein-peptide docking, Therapeutics.
About this chapter
Cite this chapter as:
B. Aarthi Rashmi, Harishchander Anandaram, S. Sachin Kumar ;Protein-Peptide Docking: An Initiation to Discover Therapeutic Peptides, Intelligent Technologies for Scientific Research and Engineering (2023) 1: 60. https://doi.org/10.2174/9789815079395123010008
DOI https://doi.org/10.2174/9789815079395123010008 |
Publisher Name Bentham Science Publisher |