Recent Advances in Biosensor Technology

Volume: 1

DNA Biosensors: Effective Tool in Biotechnology

Author(s): Arpita Mishra, Avanish Kumar Shrivastav* and Vivek Kumar Chaturvedi

Pp: 147-162 (16)

DOI: 10.2174/9789815123739123010010

* (Excluding Mailing and Handling)

Abstract

A biosensor is a device that converts a biological response into a detectable electrical signal. In recent years, biosensors have gained significant interest due to a plethora of applications in the field of disease diagnosis, detection of various environmental pollutants, food quality analysis, and pharmaceutical drug research. Among various types of biosensors, (such as enzyme-based, immunosensors, DNA biosensors, thermal and piezoelectric biosensors) DNA biosensors are being widely employed because of superior biocompatibility, thermal stability and alternative functionalization. DNA biosensors introduced in recent years include an aptamer-based sensor, molecular beacon-based biosensors, fluorescence-based sensors, hybridizationbased sensors and electrochemical-based DNA biosensors. This chapter highlights the fundamental knowledge and recent advances in the field of DNA-based biosensors. This chapter also focuses on the significance and wide application of DNAbased biosensors in the diverse areas of biotechnology and allied fields.


Keywords: Aptamers, Biosensor, Diagnosis, DNA-based, Environment, Fluorescence-based.

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