Breast Cancer: Current Trends in Molecular Research

An Overview of Breast Cancer Therapy

Author(s): Alkhansa S. Mahmoud, Zuki AB. Zakaria, Hazilawati HJ. Hamzah, Tengku Ahbrizal F.T.A. and M.N. Mohd Hezmee *

Pp: 242-258 (17)

Doi: 10.2174/9781681089522112010014

* (Excluding Mailing and Handling)


Breast cancer is the most common type of cancer among females worldwide. It is a heterogeneous disease where the treatment strategies depend on several factors, such as tumor stage, menopausal status, breast cancer oncogenes (BRCA1 or BRCA2), and hormone receptor (ER, PR, and HER2) status. Treatment of breast cancer may be neoadjuvant therapy when given before surgery or adjuvant therapy when given after surgery. Adjuvant therapy is also known as systemic therapy, where the cancer cells are treated with chemotherapy, radiotherapy, hormonal therapy, and immunotherapy. In this article, we present current therapeutic strategies and discuss the types of treatments that constitute the standard of care for breast cancer.

Keywords: Hormonal therapy, Immunotherapy, Neoadjuvant therapy, Radiotherapy, Systematic therapy.

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