Advances in Organic Synthesis

Volume: 17

Stereoselective Procedures for the Synthesis of Olefines

Author(s): Haydar Göksu * .

Pp: 53-100 (48)

DOI: 10.2174/9789815040524122170004

* (Excluding Mailing and Handling)


Olefins are molecules containing double bonds and are an active functional class. They have the potential to react easily due to the pi bonds in their structures. Therefore, olefins themselves form a biologically active class. In addition, they are pioneer molecules in obtaining different derivatives over many reaction types in organic chemistry. The presence of double bonds brings along geometric isomers (e.g., cis, trans, E, Z). The biological activities of olefins differ in geometric isomers. Therefore, stereoselectivity is important for the synthesis of olefins. In stereoselective olefin synthesis, the control is in the hands of the synthetic organic chemist. Stereoselectivity can be controlled with a correct and practical method. In this study, i) geometric isomers ii) biological activities and iii) stereoselective synthesis of olefins are focused. 

Keywords: Biological Activity, Geometric Isomer, Olefin, Stereoselective Synthesis.

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