An Overview of Food Metabolomics: CE-MS Based Targeted and Non-targeted Analysis

The safety and quality of food products, which is one of the most significant issues today, is a cause of increasing concern for consumers. For this reason, food policies are tightly determined by the governments with new conditions and regulations. Systematic monitoring of chemical pollutants such as pesticides, toxins, environmental and industrial contaminants, and residues in food products is critical in protecting public health. Capillary Electrophoresis with mass spectrometry (CE-MS) is frequently used in food analysis to ensure food safety and food quality. In this review, an updated overview of the targeted analysis of residues, contaminants, exogenous toxic ingredients, endogenous toxic ingredients, bioactive components, carbohydrates, amino acids, peptides and proteins in different food matrices through CE-MS is presented. In addition, the advantages of CE-MS based non-targeted analysis and its effectiveness in the field of food safety and quality are discussed in the light of recent studies. From a future perspective, the role of CE-MS based food metabolomics in food science is discussed together with recent developments on metabolomics applications. 

Keywords: CE-MS, Food, Food safety, Food quality, Food metabolomics, Foodomics, Targeted analysis, Non-targeted analysis.