Quick Guideline for Computational Drug Design (Revised Edition)

Secondary Structure Analyses

Author(s): Sheikh Arslan Sehgal*, Rana Adnan Tahir and Muhammad Waqas

Pp: 17-20 (4)

DOI: 10.2174/9789814998697121010006

* (Excluding Mailing and Handling)


The analyses of a secondary structure of protein always show logical insights for further studies. α-helices and β-sheets are considered as the major elements of secondary structure, which are based on hydrogen bond donor and acceptor residues interactions. The secondary elements may provide information regarding the behavior of the proteins. ProFunc tool was utilized to analyze the secondary structure of PSEN2.

Keywords: Helices, Motifs, ProFunc, Secondary structure, Sheets.

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