Abstract
The emergence of glycomics has deeply stimulated the design of new bioactive glycoclusters over the past decade. Among the increasing number of multivalent synthetic structures reported so far, cyclopeptide-based glycoclusters (CBGs) have recently shown promising interest for diverse biological applications. This chapter aims at describing the major advances in this field, with a special focus on the inhibition of carbohydrate-protein interactions and the synthetic vaccines.
Keywords: Cyclopeptide, glycocluster, oxime, combinatorial chemistry, synthetic vaccine, lectin
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