Yaws disease is an infectious disease which is caused by Treponema pallidum. It is an endemic non-venereal disease. In the tropical regions where humidity is present yaws are spread by skin to skin contact. The main camping was started to eradicate this disease by using injectable penicillin. It mainly affects children who are living in poor areas they resultantly suffered from lesions of the bone, cartilage, and skin. The reinfection risk caused by repetitive contact with those children who have an infection and they seem to be a key factor in predicting the treatment failure.