Subwavelength Optics: Theory and Technology


Author(s): Yongqi Fu

Pp: 134-154 (21)

DOI: 10.2174/978160805050510901010134

* (Excluding Mailing and Handling)


Design considerations for the metallic nanoparticles for biosensing were introduced firstly. Then the commonly used nanofabrication approaches were presented. After that, one important application, localized surface plasmon polritons (LSPR)-based immunoassay using the nanoparticles array was illustrated. Finally, the LSPR-related photothermal therapy was briefly described.

Metallic nanoparticles array being used as sensors for biosensing is a major application of nanophotonic devices, especially for the localized surface plasmon resonant (LSPR) effect-based nano-biosensors. It is an important approach for immunoassay. Numerous biosamples can be detected by means of the LSPR-based nano-biosensors such as biotin,[1] amyloid-derived diffusible ligands,[2] and Staphylococcus aureus enterotoxin B etc.[3] It becomes appealing for biological researchers due to its advantages of portable, cost effective, light weight, small volume, and simple system in comparison to the conventional SPR system, e.g., Bicore system.

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