Reviews in Pharmaceutical & Biomedical Analysis

Control of the Level of Apoptosis by Different Analytical Techniques

Author(s): Małgorzata Starek, Monika Dąbrowska and Jerzy Skuciński

Pp: 108-113 (6)

DOI: 10.2174/978160805190811001010108

* (Excluding Mailing and Handling)


The process of programmed cell death, or apoptosis is characterized by distinct morphological and biochemical mechanisms. Inappropriate apoptosis (too little or too much) is a factor in many human conditions including neurodegenerative diseases, autoimmune disorders and many types of cancer. Although many assays for apoptosis detection have been established so far, precise differentiating apoptosis and necrosis in single cells is still a hallenge. In this study we present the most common analytical techniques for the control of the level of apoptosis.

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